Function and Biology Details
Reaction catalysed:
ATP = 3',5'-cyclic AMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Bacterial exotoxin B
- Anthrax toxin, lethal/endema factor
- PA14 domain
- Protective antigen, domain 4
- Clostridial binary toxin B/anthrax toxin PA, domain 3
- Protective antigen, heptamerisation domain
- Protective antigen, heptamerisation domain superfamily
- Protective antigen, Ca-binding domain
7 more domains
Structure analysis Details
Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146586 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protective antigen
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 735 amino acids
Theoretical weight: 82.77 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains:
Length: 735 amino acids
Theoretical weight: 82.77 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical:
P13423 (Residues: 30-764; Coverage: 100%)
Sequence domains:
Calmodulin-sensitive adenylate cyclase
Molecule details ›
Chains: H, I
Length: 767 amino acids
Theoretical weight: 88.96 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
Sequence domains:
Length: 767 amino acids
Theoretical weight: 88.96 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
- Canonical: P40136 (Residues: 34-800; Coverage: 100%)
Sequence domains:
