› 6xmt

Electron Microscopy
3.3Å resolution

Structure of P5A-ATPase Spf1, BeF3-bound form

Released:
DOI: 10.2210/pdb6xmt/pdb
PDB entry 6xmt coloured by chain, front view.
PDB entry 6xmt coloured by chain, side view.
PDB entry 6xmt coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
McKenna MJ, Sim SI, Ordureau A, Wei L, Harper JW, Shao S, Park E
Science 369 (2020)
PMID: 32973005
Related structures: EMD-22263

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153990 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoplasmic reticulum transmembrane helix translocase Chain: A
Molecule details ›
Chain: A
Length: 1239 amino acids
Theoretical weight: 137.57 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Saccharomyces cerevisiae BY4741
UniProt:
  • Canonical: P39986 (Residues: 1-1215; Coverage: 100%)
Gene names: COD1, SPF1, YEL031W
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand BEF 1 x BEF
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-22263
Expression system: Saccharomyces cerevisiae BY4741

Quick links

Citations

14 review citations

The mechanisms of integral membrane protein biogenesis.
Hegde et al. (2022)
13 more

3 mentions without citation

The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase.
McKenna et al. (2020)
2 more