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Fo domain of Ovine ATP synthase

Electron Microscopy
3.76Å resolution
PDB entry 6za9 coloured by chain, front view.
PDB entry 6za9 coloured by chain, side view.
PDB entry 6za9 coloured by chain, top view.
Source organism: Ovis aries
Assembly composition:
hetero heptadecamer (preferred)
Entry contents: 10 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero heptadecamer
Accessible surface area: 54543.9 Å2
Buried surface area: 69672.52 Å2
Dissociation area: 696.06 Å2
Dissociation energy (ΔGdiss): 6.51 kcal/mol
Dissociation entropy (TΔSdiss): 10.66 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-105816

Macromolecules

ATP synthase F(0) complex subunit C1, mitochondrial
Chains: 1, 2, 3, 4, 5, 6, 7, 8
Length: 136 amino acids
Theoretical weight: 14.2 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: P17605 (Residues: 1-136; Coverage: 100%)
Gene names: ATP5G1, ATP5MC1
Pfam: ATP synthase subunit C
InterPro:
ATP synthase F(0) complex subunit C1, mitochondrial in PDB entry 6za9, assembly 1, front view.
ATP synthase F(0) complex subunit C1, mitochondrial in PDB entry 6za9, assembly 1, side view.
ATP synthase F(0) complex subunit C1, mitochondrial in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit b
Chain: K
Length: 256 amino acids
Theoretical weight: 28.84 KDa
Source organism: Ovis aries
InterPro:
ATP synthase subunit b in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit b in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit b in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit d, mitochondrial
Chain: M
Length: 161 amino acids
Theoretical weight: 18.75 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PP37 (Residues: 1-161; Coverage: 100%)
Gene name: ATP5PD
Pfam: ATP synthase D chain, mitochondrial (ATP5H)
InterPro:
ATP synthase subunit d, mitochondrial in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit d, mitochondrial in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit d, mitochondrial in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit a
Chain: N
Length: 226 amino acids
Theoretical weight: 24.81 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78752 (Residues: 1-226; Coverage: 100%)
Gene names: ATP6, ATPASE6, MT-ATP6, MTATP6
Pfam: ATP synthase A chain
InterPro:
ATP synthase subunit a in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit a in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit a in PDB entry 6za9, assembly 1, top view.
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ATP synthase membrane subunit K, mitochondrial
Chain: O
Length: 58 amino acids
Theoretical weight: 6.44 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: A0A6P7DV05 (Residues: 1-58; Coverage: 100%)
Gene name: ATP5MK
Pfam: ATP synthase regulation
InterPro: ATP synthase membrane subunit K
ATP synthase membrane subunit K, mitochondrial in PDB entry 6za9, assembly 1, front view.
ATP synthase membrane subunit K, mitochondrial in PDB entry 6za9, assembly 1, side view.
ATP synthase membrane subunit K, mitochondrial in PDB entry 6za9, assembly 1, top view.
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ATP synthase membrane subunit 6.8PL
Chain: P
Length: 60 amino acids
Theoretical weight: 6.85 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5P913 (Residues: 1-60; Coverage: 100%)
Pfam: Mitochondrial proteolipid
InterPro: ATP synthase subunit ATP5MJ, mitochondrial
ATP synthase membrane subunit 6.8PL in PDB entry 6za9, assembly 1, front view.
ATP synthase membrane subunit 6.8PL in PDB entry 6za9, assembly 1, side view.
ATP synthase membrane subunit 6.8PL in PDB entry 6za9, assembly 1, top view.
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ATP synthase protein 8
Chain: Q
Length: 66 amino acids
Theoretical weight: 7.92 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: O78751 (Residues: 1-66; Coverage: 100%)
Gene names: ATP8, ATPASE8, MT-ATP8, MTATP8
Pfam: ATP synthase protein 8
InterPro:
ATP synthase protein 8 in PDB entry 6za9, assembly 1, front view.
ATP synthase protein 8 in PDB entry 6za9, assembly 1, side view.
ATP synthase protein 8 in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit f, mitochondrial
Chain: R
Length: 88 amino acids
Theoretical weight: 10.32 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5QB48 (Residues: 6-93; Coverage: 95%)
Gene name: LOC101109584
Pfam: Mitochondrial F1F0-ATP synthase, subunit f
InterPro: Mitochondrial F1-F0 ATP synthase subunit F, predicted
ATP synthase subunit f, mitochondrial in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit f, mitochondrial in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit f, mitochondrial in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit
Chain: S
Length: 103 amino acids
Theoretical weight: 11.43 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5Q5U7 (Residues: 1-103; Coverage: 100%)
Gene name: LOC101118348
Pfam: Mitochondrial ATP synthase g subunit
InterPro:
ATP synthase subunit in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit in PDB entry 6za9, assembly 1, top view.
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ATP synthase subunit e, mitochondrial
Chain: T
Length: 71 amino acids
Theoretical weight: 8.34 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: W5PF18 (Residues: 1-37, 38-70; Coverage: 100%)
Gene name: LOC101102454
Pfam: ATP synthase E chain
InterPro: ATP synthase, F0 complex, subunit E, mitochondrial
ATP synthase subunit e, mitochondrial in PDB entry 6za9, assembly 1, front view.
ATP synthase subunit e, mitochondrial in PDB entry 6za9, assembly 1, side view.
ATP synthase subunit e, mitochondrial in PDB entry 6za9, assembly 1, top view.
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