› › Structure analysis

Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)

Electron Microscopy
3Å resolution
PDB entry 6zox coloured by chain, front view.
PDB entry 6zox coloured by chain, side view.
PDB entry 6zox coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: SARS-CoV-2 post-fusion S2 Spike complex
hide full assembly name
Multimeric state: homo trimer
Accessible surface area: 130140.57 Å2
Buried surface area: 43816.11 Å2
Dissociation area: 15,768.33 Å2
Dissociation energy (ΔGdiss): 136.87 kcal/mol
Dissociation entropy (TΔSdiss): 37.74 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-144650
Complex Portal ID: CPX-7043

Macromolecules

Spike glycoprotein
Chains: A, B, C
Length: 1247 amino acids
Theoretical weight: 138.36 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-1211; Coverage: 95%)
Gene names: 2, S
Pfam:
InterPro:
Spike glycoprotein in PDB entry 6zox, assembly 1, front view.
Spike glycoprotein in PDB entry 6zox, assembly 1, side view.
Spike glycoprotein in PDB entry 6zox, assembly 1, top view.
PDBe-KB: UniProt Coverage View: P0DTC2  
112471002003004005006007008009001,0001,1001,200
 
5001000
UniProt
P0DTC2
PRO_0000449647
PRO_0000449648
PRO_0000449649
Chains
Domains
Secondary structure
Flexibility predictions
Ligand binding sites
Interaction interfaces
Molecule details ›

Search similar proteins

Quick links