Assemblies
Multimeric state:
hetero 51-mer
Accessible surface area:
630126.61 Å2
Buried surface area:
257259.22 Å2
Dissociation area:
1,978.96
Å2
Dissociation energy (ΔGdiss):
-4.65
kcal/mol
Dissociation entropy (TΔSdiss):
25.63
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-104449
Macromolecules
Chain: a
Length: 216 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S2
InterPro:
Length: 216 amino acids
Theoretical weight: 24.26 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P08865 (Residues: 2-217; Coverage: 73%)
Pfam: Ribosomal protein S2
InterPro:
Chain: p
Length: 211 amino acids
Theoretical weight: 24.56 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal S3Ae family
InterPro:
Length: 211 amino acids
Theoretical weight: 24.56 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P61247 (Residues: 23-233; Coverage: 80%)
Pfam: Ribosomal S3Ae family
InterPro:
Chain: d
Length: 216 amino acids
Theoretical weight: 23.86 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 216 amino acids
Theoretical weight: 23.86 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P15880 (Residues: 60-275; Coverage: 74%)
Pfam:
InterPro:
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS5, eukaryotic/archaeal
- Small ribosomal subunit protein uS5, N-terminal
- Small ribosomal subunit protein uS5, N-terminal, conserved site
- Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
- Ribosomal protein uS5 domain 2-type superfamily
- Small ribosomal subunit protein uS5, C-terminal
Chain: Q
Length: 101 amino acids
Theoretical weight: 11.65 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S26e
InterPro:
Length: 101 amino acids
Theoretical weight: 11.65 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62854 (Residues: 2-102; Coverage: 88%)
Pfam: Ribosomal protein S26e
InterPro:
Chain: q
Length: 255 amino acids
Theoretical weight: 28.89 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 255 amino acids
Theoretical weight: 28.89 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62701 (Residues: 2-256; Coverage: 97%)
Pfam:
InterPro:
- RNA-binding S4 domain superfamily
- RNA-binding S4 domain
- Small ribosomal subunit protein eS4
- Small ribosomal subunit protein eS4, N-terminal
- Small ribosomal subunit protein eS4, N-terminal, conserved site
- Small ribosomal subunit protein eS4, central region
- Small ribosomal subunit protein eS4, central domain superfamily
- Large ribosomal subunit protein uL2, domain 2
- Small ribosomal subunit protein eS4, KOW domain
- KOW
- Small ribosomal subunit protein eS4, C-terminal domain
Chain: W
Length: 24 amino acids
Theoretical weight: 3.34 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L41
InterPro: Large ribosomal subunit protein eS32
Length: 24 amino acids
Theoretical weight: 3.34 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62945 (Residues: 1-24; Coverage: 96%)
Pfam: Ribosomal protein L41
InterPro: Large ribosomal subunit protein eS32
Chain: r
Length: 222 amino acids
Theoretical weight: 25.61 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S6e
InterPro:
Length: 222 amino acids
Theoretical weight: 25.61 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62753 (Residues: 2-223; Coverage: 89%)
Pfam: Ribosomal protein S6e
InterPro:
Chain: s
Length: 181 amino acids
Theoretical weight: 20.79 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S7e
InterPro:
Length: 181 amino acids
Theoretical weight: 20.79 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62081 (Residues: 13-193; Coverage: 93%)
Pfam: Ribosomal protein S7e
InterPro:
Chain: t
Length: 205 amino acids
Theoretical weight: 23.95 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S8e
InterPro:
Length: 205 amino acids
Theoretical weight: 23.95 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62241 (Residues: 2-206; Coverage: 99%)
Pfam: Ribosomal protein S8e
InterPro:
Chain: c
Length: 180 amino acids
Theoretical weight: 21.28 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 180 amino acids
Theoretical weight: 21.28 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46781 (Residues: 2-181; Coverage: 93%)
Pfam:
InterPro:
Chain: n
Length: 144 amino acids
Theoretical weight: 16.91 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 144 amino acids
Theoretical weight: 16.91 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62280 (Residues: 4-147; Coverage: 91%)
Pfam:
InterPro:
Chain: m
Length: 149 amino acids
Theoretical weight: 17.06 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 149 amino acids
Theoretical weight: 17.06 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62277 (Residues: 2-150; Coverage: 99%)
Pfam:
InterPro:
Chain: i
Length: 125 amino acids
Theoretical weight: 13.46 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S11
InterPro:
Length: 125 amino acids
Theoretical weight: 13.46 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: A0A2R8Y811 (Residues: 26-150; Coverage: 83%)
Pfam: Ribosomal protein S11
InterPro:
Chain: y
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S21e
InterPro:
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P63220 (Residues: 1-82; Coverage: 99%)
Pfam: Ribosomal protein S21e
InterPro:
Chain: f
Length: 129 amino acids
Theoretical weight: 14.73 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S8
InterPro:
Length: 129 amino acids
Theoretical weight: 14.73 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62244 (Residues: 2-130; Coverage: 99%)
Pfam: Ribosomal protein S8
InterPro:
Chain: j
Length: 139 amino acids
Theoretical weight: 15.37 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S12/S23
InterPro:
Length: 139 amino acids
Theoretical weight: 15.37 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62266 (Residues: 2-140; Coverage: 97%)
Pfam: Ribosomal protein S12/S23
InterPro:
Chain: z
Length: 122 amino acids
Theoretical weight: 14.26 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S24e
InterPro:
Length: 122 amino acids
Theoretical weight: 14.26 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: E7ETK0 (Residues: 5-126; Coverage: 93%)
Pfam: Ribosomal protein S24e
InterPro:
Chain: R
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S27
InterPro:
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P42677 (Residues: 2-83; Coverage: 98%)
Pfam: Ribosomal protein S27
InterPro:
Chain: T
Length: 44 amino acids
Theoretical weight: 5.07 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S30
InterPro: Small ribosomal subunit protein eS30
Length: 44 amino acids
Theoretical weight: 5.07 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62861 (Residues: 81-124; Coverage: 33%)
Pfam: Ribosomal protein S30
InterPro: Small ribosomal subunit protein eS30
Chain: w
Length: 130 amino acids
Theoretical weight: 15.04 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal S17
InterPro:
Length: 130 amino acids
Theoretical weight: 15.04 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P08708 (Residues: 2-131; Coverage: 96%)
Pfam: Ribosomal S17
InterPro:
Chain: g
Length: 138 amino acids
Theoretical weight: 15.64 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S9/S16
InterPro:
Length: 138 amino acids
Theoretical weight: 15.64 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62249 (Residues: 9-146; Coverage: 95%)
Pfam: Ribosomal protein S9/S16
InterPro:
Chain: b
Length: 224 amino acids
Theoretical weight: 24.87 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 224 amino acids
Theoretical weight: 24.87 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P23396 (Residues: 4-227; Coverage: 92%)
Pfam:
InterPro:
- K homology domain-like, alpha/beta
- Small ribosomal subunit protein uS3, eukaryotic/archaeal
- K homology domain superfamily, prokaryotic type
- K Homology domain, type 2
- Ribosomal protein S3, C-terminal domain superfamily
- Small ribosomal subunit protein uS3, C-terminal
- Small ribosomal subunit protein uS3, conserved site
Chain: e
Length: 189 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S7p/S5e
InterPro:
Length: 189 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46782 (Residues: 16-204; Coverage: 93%)
Pfam: Ribosomal protein S7p/S5e
InterPro:
Chain: u
Length: 95 amino acids
Theoretical weight: 11.37 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Plectin/S10 domain
InterPro:
Length: 95 amino acids
Theoretical weight: 11.37 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P46783 (Residues: 1-95; Coverage: 58%)
Pfam: Plectin/S10 domain
InterPro:
Chain: v
Length: 116 amino acids
Theoretical weight: 12.95 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Length: 116 amino acids
Theoretical weight: 12.95 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P25398 (Residues: 14-129; Coverage: 88%)
Pfam: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
InterPro:
Chain: o
Length: 119 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S19
InterPro:
Length: 119 amino acids
Theoretical weight: 14.01 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62841 (Residues: 15-133; Coverage: 82%)
Pfam: Ribosomal protein S19
InterPro:
Chain: k
Length: 140 amino acids
Theoretical weight: 16.5 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S13/S18
InterPro:
Length: 140 amino acids
Theoretical weight: 16.5 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62269 (Residues: 3-142; Coverage: 92%)
Pfam: Ribosomal protein S13/S18
InterPro:
Chain: x
Length: 141 amino acids
Theoretical weight: 15.56 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S19e
InterPro:
Length: 141 amino acids
Theoretical weight: 15.56 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P39019 (Residues: 2-142; Coverage: 97%)
Pfam: Ribosomal protein S19e
InterPro:
Chain: h
Length: 98 amino acids
Theoretical weight: 11.19 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S10p/S20e
InterPro:
Length: 98 amino acids
Theoretical weight: 11.19 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P60866 (Residues: 19-116; Coverage: 82%)
Pfam: Ribosomal protein S10p/S20e
InterPro:
Chain: P
Length: 70 amino acids
Theoretical weight: 7.94 KDa
Source organism: Homo sapiens
UniProt:
Pfam: S25 ribosomal protein
InterPro:
Length: 70 amino acids
Theoretical weight: 7.94 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62851 (Residues: 44-113; Coverage: 56%)
Pfam: S25 ribosomal protein
InterPro:
Chain: S
Length: 61 amino acids
Theoretical weight: 6.88 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S28e
InterPro:
Length: 61 amino acids
Theoretical weight: 6.88 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62857 (Residues: 8-68; Coverage: 88%)
Pfam: Ribosomal protein S28e
InterPro:
Chain: l
Length: 54 amino acids
Theoretical weight: 6.44 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S14p/S29e
InterPro:
Length: 54 amino acids
Theoretical weight: 6.44 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62273 (Residues: 2-55; Coverage: 96%)
Pfam: Ribosomal protein S14p/S29e
InterPro:
Chain: U
Length: 62 amino acids
Theoretical weight: 7.26 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Ribosomal protein S27a
InterPro:
Length: 62 amino acids
Theoretical weight: 7.26 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P62979 (Residues: 88-149; Coverage: 40%)
Pfam: Ribosomal protein S27a
InterPro:
Chain: V
Length: 309 amino acids
Theoretical weight: 34.22 KDa
Source organism: Homo sapiens
UniProt:
Pfam: WD domain, G-beta repeat
InterPro:
Length: 309 amino acids
Theoretical weight: 34.22 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P63244 (Residues: 4-312; Coverage: 98%)
Pfam: WD domain, G-beta repeat
InterPro:
Chain: I
Length: 316 amino acids
Theoretical weight: 35.35 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 316 amino acids
Theoretical weight: 35.35 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q13347 (Residues: 1-316; Coverage: 97%)
Pfam:
InterPro:
Chain: B
Length: 566 amino acids
Theoretical weight: 65.9 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 566 amino acids
Theoretical weight: 65.9 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P55884 (Residues: 180-745; Coverage: 70%)
Pfam:
InterPro:
- Eukaryotic translation initiation factor 3 subunit B
- Nucleotide-binding alpha-beta plait domain superfamily
- eIF3B, RNA recognition motif
- RNA recognition motif domain
- RNA-binding domain superfamily
- WD40/YVTN repeat-like-containing domain superfamily
- Translation initiation factor, beta propellor-like domain
Chain: A
Length: 722 amino acids
Theoretical weight: 85.56 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 722 amino acids
Theoretical weight: 85.56 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q14152 (Residues: 4-725; Coverage: 52%)
Pfam:
InterPro:
Chain: C
Length: 743 amino acids
Theoretical weight: 86.2 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 743 amino acids
Theoretical weight: 86.2 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: B4DVU3 (Residues: 1-129, 130-761; Coverage: 98%)
Pfam:
InterPro:
Chain: E
Length: 429 amino acids
Theoretical weight: 50.44 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
Length: 429 amino acids
Theoretical weight: 50.44 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P60228 (Residues: 2-430; Coverage: 96%)
Pfam:
- PCI domain
- eIF3 subunit 6 N terminal domain
- Eukaryotic translation initiation factor 3 subunit E, C-terminal
Chain: F
Length: 269 amino acids
Theoretical weight: 29.84 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 269 amino acids
Theoretical weight: 29.84 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: O00303 (Residues: 89-357; Coverage: 75%)
Pfam:
InterPro:
Chain: H
Length: 318 amino acids
Theoretical weight: 36.96 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 318 amino acids
Theoretical weight: 36.96 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: O15372 (Residues: 35-352; Coverage: 90%)
Pfam:
InterPro:
Chain: K
Length: 217 amino acids
Theoretical weight: 24.95 KDa
Source organism: Homo sapiens
UniProt:
Pfam: CSN8/PSMD8/EIF3K family
InterPro:
Length: 217 amino acids
Theoretical weight: 24.95 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q9UBQ5 (Residues: 2-218; Coverage: 100%)
Pfam: CSN8/PSMD8/EIF3K family
InterPro:
Chain: L
Length: 372 amino acids
Theoretical weight: 44.17 KDa
Source organism: Homo sapiens
UniProt:
Pfam: RNA polymerase I-associated factor PAF67
InterPro:
Length: 372 amino acids
Theoretical weight: 44.17 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: Q9Y262 (Residues: 181-552; Coverage: 66%)
Pfam: RNA polymerase I-associated factor PAF67
InterPro:
Chain: 1
Length: 595 amino acids
Theoretical weight: 66.97 KDa
Source organism: Homo sapiens
UniProt:
Pfam:
InterPro:
Length: 595 amino acids
Theoretical weight: 66.97 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P61221 (Residues: 4-598; Coverage: 99%)
Pfam:
InterPro:
- RLI1
- P-loop containing nucleoside triphosphate hydrolase
- RNase L inhibitor RLI-like, possible metal-binding domain
- 4Fe-4S ferredoxin-type, iron-sulphur binding domain
- 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
- RLI, domain 1
- ABC transporter-like, ATP-binding domain
- AAA+ ATPase domain
- ABC transporter-like, conserved site
Chain: N
Length: 91 amino acids
Theoretical weight: 10.39 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Translation initiation factor SUI1
InterPro:
Length: 91 amino acids
Theoretical weight: 10.39 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: P41567 (Residues: 23-113; Coverage: 81%)
Pfam: Translation initiation factor SUI1
InterPro:
Chain: D
Length: 527 amino acids
Theoretical weight: 61.49 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
InterPro: Eukaryotic translation initiation factor 3 subunit D
Length: 527 amino acids
Theoretical weight: 61.49 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: O15371 (Residues: 1-527; Coverage: 96%)
Pfam: Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)
InterPro: Eukaryotic translation initiation factor 3 subunit D
Chain: Y
Length: 78 amino acids
Theoretical weight: 5.56 KDa
Source organism: Homo sapiens
Length: 78 amino acids
Theoretical weight: 5.56 KDa
Source organism: Homo sapiens
Chains: G, J
Length: 258 amino acids
Theoretical weight: 29.11 KDa
Source organism: Homo sapiens
UniProt:
Pfam: Translation initiation factor eIF3 subunit
InterPro:
Length: 258 amino acids
Theoretical weight: 29.11 KDa
Source organism: Homo sapiens
UniProt:
- Canonical: O75822 (Residues: 1-258; Coverage: 100%)
Pfam: Translation initiation factor eIF3 subunit
InterPro:
Name:
18S Ribosomal RNA
Representative chains: 2
Length: 1720 nucleotides
Theoretical weight: 555.21 KDa
Rfam: Eukaryotic small subunit ribosomal RNA
Representative chains: 2
Length: 1720 nucleotides
Theoretical weight: 555.21 KDa
Rfam: Eukaryotic small subunit ribosomal RNA