› › Structure analysis

Complex between SMAD2 MH2 domain and peptide from Ski corepressor

X-ray diffraction
2.03Å resolution
PDB entry 6zvq coloured by chain, front view.
PDB entry 6zvq coloured by chain, side view.
PDB entry 6zvq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero hexamer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: SMAD2 homotrimer and Ski oncogene
hide full assembly name
Multimeric state: hetero hexamer
Accessible surface area: 25529.32 Å2
Buried surface area: 23283.1 Å2
Dissociation area: 2,885.85 Å2
Dissociation energy (ΔGdiss): 32.1 kcal/mol
Dissociation entropy (TΔSdiss): 27.31 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-146310

Macromolecules

Mothers against decapentaplegic homolog 2
Chain: A
Length: 227 amino acids
Theoretical weight: 25.54 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q15796 (Residues: 241-467; Coverage: 49%)
Gene names: MADH2, MADR2, SMAD2
Pfam: MH2 domain
InterPro:
Mothers against decapentaplegic homolog 2 in PDB entry 6zvq, assembly 1, front view.
Mothers against decapentaplegic homolog 2 in PDB entry 6zvq, assembly 1, side view.
Mothers against decapentaplegic homolog 2 in PDB entry 6zvq, assembly 1, top view.
Molecule details ›

Search similar proteins

Ski oncogene
Chain: B
Length: 35 amino acids
Theoretical weight: 3.85 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P12755 (Residues: 11-45; Coverage: 5%)
Gene name: SKI
Ski oncogene in PDB entry 6zvq, assembly 1, front view.
Ski oncogene in PDB entry 6zvq, assembly 1, side view.
Ski oncogene in PDB entry 6zvq, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links