7abh

Electron Microscopy
4.5Å resolution

Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexadecamer (preferred)
PDBe Complex ID:
PDB-CPX-130106 (preferred)
Entry contents:
14 distinct polypeptide molecules
2 distinct RNA molecules
Macromolecules (16 distinct):
Cell division cycle 5-like protein Chain: L
Molecule details ›
Chain: L
Length: 802 amino acids
Theoretical weight: 92.41 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q99459 (Residues: 1-802; Coverage: 100%)
Gene names: CDC5L, KIAA0432, PCDC5RP
Sequence domains:
PHD finger-like domain-containing protein 5A Chain: y
Molecule details ›
Chain: y
Length: 110 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q7RTV0 (Residues: 1-110; Coverage: 100%)
Gene name: PHF5A
Sequence domains: PHF5-like protein
Splicing factor 3A subunit 2 Chain: F
Splicing factor 3A subunit 3 Chain: 4
Splicing factor 3B subunit 1 Chain: u
Splicing factor 3B subunit 2 Chain: T
Splicing factor 3B subunit 3 Chain: E
Splicing factor 3B subunit 4 Chain: w
Splicing factor 3B subunit 5 Chain: x
Splicing factor 3B subunit 6 Chain: z
Smad nuclear-interacting protein 1 Chain: 0
RNA-binding motif protein, X-linked 2 Chain: 1
Serine/arginine repetitive matrix protein 1 Chain: Y
DNA/RNA-binding protein KIN17 Chain: 7
MINX M3 pre-mRNA Chain: Z
U2 snRNA Chain: 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.5Å
Relevant EMDB volumes: EMD-11696