› 7mmo

X-ray diffraction
2.43Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-534848 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
LY-CoV1404 Fab heavy chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 223 amino acids
Theoretical weight: 24.16 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
LY-CoV1404 Fab light chain Chains: B, E
Molecule details ›
Chains: B, E
Length: 215 amino acids
Theoretical weight: 22.95 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Spike protein S1 Chains: C, F
Molecule details ›
Chains: C, F
Length: 205 amino acids
Theoretical weight: 23.17 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P0DTC2 (Residues: 329-527; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
1 modified residue:
Ligand PCA 2 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P212121
Unit cell:
a: 73.094Å b: 107.692Å c: 190.472Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.226 0.253
Expression system: Cricetulus griseus

Quick links

Citations

1 citations in other articles

Differential Expression of Nuclear-Encoded Mitochondrial Protein Genes of ATP Synthase Across Different Tissues of Female Buffalo.
Sadeesh et al. (2024)

53 mentions without citation

Monoclonal antibody therapies against SARS-CoV-2.
Focosi et al. (2022)
52 more