Function and Biology

Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa

Source organism: Pseudomonas aeruginosa PAO1
Biochemical function: transmembrane transporter activity
Biological process: transmembrane transport
Cellular component: membrane

Sequence family

Pfam Protein family (Pfam)
PF02321
Domain description: Outer membrane efflux protein
Occurring in:
  1. Outer membrane protein OprM
The deposited structure of PDB entry 7akz contains 4 copies of Pfam domain PF02321 (Outer membrane efflux protein) in Outer membrane protein OprM. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR003423
Domain description: Outer membrane efflux protein
Occurring in:
  1. Outer membrane protein OprM
IPR010131
Domain description: RND efflux system, outer membrane lipoprotein, NodT
Occurring in:
  1. Outer membrane protein OprM