Structure analysis

Crystal Structure of an Anti-Plasminogen Activator Inhibitor-1 (PAI-1) scFv antibody fragment (scFv-33H1F7)

X-ray diffraction
1.8Å resolution
Source organism: Mus musculus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 10215.06 Å2
Buried surface area: 338.81 Å2
Dissociation area: 71.14 Å2
Dissociation energy (ΔGdiss): 10.11 kcal/mol
Dissociation entropy (TΔSdiss): 0.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214316
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 10557.59 Å2
Buried surface area: 337.16 Å2
Dissociation area: 72.21 Å2
Dissociation energy (ΔGdiss): 10.82 kcal/mol
Dissociation entropy (TΔSdiss): 0.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214316
Assembly 3
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Multimeric state: monomeric
Accessible surface area: 10401.71 Å2
Buried surface area: 325.55 Å2
Dissociation area: 67.1 Å2
Dissociation energy (ΔGdiss): 9.16 kcal/mol
Dissociation entropy (TΔSdiss): 0.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214316
Assembly 4
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Multimeric state: monomeric
Accessible surface area: 10632.7 Å2
Buried surface area: 329.04 Å2
Dissociation area: 65.84 Å2
Dissociation energy (ΔGdiss): 9.44 kcal/mol
Dissociation entropy (TΔSdiss): 0.59 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-214316

Macromolecules

Chains: A, B, C, D
Length: 242 amino acids
Theoretical weight: 25.95 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
InterPro:

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