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Crystal structure of the phosphodiesterase domain of Salpingoeca rosetta rhodopsin phosphodiesterase

X-ray diffraction
2.1Å resolution
PDB entry 7d7p coloured by chain, front view.
PDB entry 7d7p coloured by chain, side view.
PDB entry 7d7p coloured by chain, top view.
Source organism: Salpingoeca rosetta
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Phosphodiesterase
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Multimeric state: homo dimer
Accessible surface area: 29213.17 Å2
Buried surface area: 3825.4 Å2
Dissociation area: 363.27 Å2
Dissociation energy (ΔGdiss): -19.93 kcal/mol
Dissociation entropy (TΔSdiss): 12.72 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-123407

Macromolecules

Phosphodiesterase
Chain: A
Length: 365 amino acids
Theoretical weight: 42.02 KDa
Source organism: Salpingoeca rosetta
Expression system: Homo sapiens
UniProt:
  • Canonical: F2TZN0 (Residues: 346-703; Coverage: 51%)
Gene name: PTSG_02023
Pfam: 3'5'-cyclic nucleotide phosphodiesterase
InterPro:
Phosphodiesterase in PDB entry 7d7p, assembly 1, front view.
Phosphodiesterase in PDB entry 7d7p, assembly 1, side view.
Phosphodiesterase in PDB entry 7d7p, assembly 1, top view.
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