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Mechanosensitive channel MscS K180R mutant

Electron Microscopy
2.5Å resolution
PDB entry 7dlu coloured by chain, front view.
PDB entry 7dlu coloured by chain, side view.
PDB entry 7dlu coloured by chain, top view.
Source organism: Pseudomonas aeruginosa PAO1
Assembly composition:
homo heptamer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Small-conductance mechanosensitive channel
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Multimeric state: homo heptamer
Accessible surface area: 87169.57 Å2
Buried surface area: 36834.13 Å2
Dissociation area: 18,417.07 Å2
Dissociation energy (ΔGdiss): 230.01 kcal/mol
Dissociation entropy (TΔSdiss): 91 kcal/mol
Symmetry number: 7
PDBe Complex ID: PDB-CPX-191042

Macromolecules

Small-conductance mechanosensitive channel
Chains: A, B, C, D, E, F, G
Length: 278 amino acids
Theoretical weight: 29.87 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HW12 (Residues: 1-278; Coverage: 100%)
Gene name: PA4394
Pfam:
InterPro:
Small-conductance mechanosensitive channel in PDB entry 7dlu, assembly 1, front view.
Small-conductance mechanosensitive channel in PDB entry 7dlu, assembly 1, side view.
Small-conductance mechanosensitive channel in PDB entry 7dlu, assembly 1, top view.
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