› 7e4j

X-ray diffraction
1.63Å resolution

X-ray crystal structure of VapB12 antitoxin from mycobacterium tuberculosis in space group P41.

Released:
DOI: 10.2210/pdb7e4j/pdb
PDB entry 7e4j coloured by chain, front view.
PDB entry 7e4j coloured by chain, side view.
PDB entry 7e4j coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Pratap S, Megta AK, Talwar S, Chandresh S, Pandey AK, Krishnan V

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161669 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative antitoxin VapB12 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 44 amino acids
Theoretical weight: 4.94 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P9WJ53 (Residues: 1-44; Coverage: 59%)
Gene names: Rv1721c, vapB12
Sequence domains: Antitoxin FitA-like, ribbon-helix-helix

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P41
Unit cell:
a: 34.66Å b: 34.66Å c: 162.227Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.174 0.172 0.218
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

Quick links