7ell

Electron Microscopy
3.8Å resolution

In situ structure of capping enzyme lambda2, penetration protein mu1 of mammalian reovirus capsid asymmetric unit.

Released:

Function and Biology Details

Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 21-mer (preferred)
PDBe Complex ID:
PDB-CPX-145652 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Outer capsid protein mu-1N Chains: A, B, C, D, E, F, G, H, I, J
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J
Length: 41 amino acids
Theoretical weight: 4.05 KDa
Source organism: Mammalian orthoreovirus 3
UniProt:
  • Canonical: P11078 (Residues: 2-42; Coverage: 6%)
Gene name: M2
Outer capsid protein mu-1 Chains: a, b, c, d, e, f, g, h, i, j
Molecule details ›
Chains: a, b, c, d, e, f, g, h, i, j
Length: 666 amino acids
Theoretical weight: 72.23 KDa
Source organism: Mammalian orthoreovirus 3
UniProt:
  • Canonical: P11078 (Residues: 43-708; Coverage: 94%)
Gene name: M2
Sequence domains: Reovirus major virion structural protein Mu-1/Mu-1C (M2)

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.8Å
Relevant EMDB volumes: EMD-31184