EC 2.3.2.27: RING-type E3 ubiquitin transferase
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
- RING E3 ligase
- Ubiquitin transferase RING E3
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Protein families (Pfam)![The deposited structure of PDB entry 7hmq contains 1 copy of Pfam domain PF00622 (SPRY domain) in E3 ubiquitin-protein ligase TRIM21. Showing 1 copy in chain A [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/7hmq_1_B_Pfam_PF00622_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7hmq</span> contains 1 copy of Pfam domain <span class='highlight'>PF00622 (SPRY domain)</span> in <span class='highlight'>E3 ubiquitin-protein ligase TRIM21</span>. Showing 1 copy in chain <span class='highlight'>A [auth B]</span>.")
![The deposited structure of PDB entry 7hmq contains 1 copy of Pfam domain PF13765 (SPRY-associated domain) in E3 ubiquitin-protein ligase TRIM21. Showing 1 copy in chain A [auth B].](https://www.ebi.ac.uk/pdbe/static/entry/7hmq_1_B_Pfam_PF13765_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7hmq</span> contains 1 copy of Pfam domain <span class='highlight'>PF13765 (SPRY-associated domain)</span> in <span class='highlight'>E3 ubiquitin-protein ligase TRIM21</span>. Showing 1 copy in chain <span class='highlight'>A [auth B]</span>.")