Structure analysis

DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) (FOUR-DAY SOAK)

X-ray diffraction
3.1Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero trimer (preferred)
Entry contents: 1 distinct polypeptide molecule
2 distinct DNA molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 19068.0 Å2
Buried surface area: 2032.65 Å2
Dissociation area: 534.45 Å2
Dissociation energy (ΔGdiss): 7.74 kcal/mol
Dissociation entropy (TΔSdiss): 8.41 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-121287

Macromolecules

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Name: DNA (5'-D(*CP*AP*TP*CP*TP*GP*T)-3')
Representative chains: T
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 7 nucleotides
Theoretical weight: 2.09 KDa

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Name: DNA (5'-D(*CP*AP*GP*AP*TP*G)-3')
Representative chains: P
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 6 nucleotides
Theoretical weight: 1.83 KDa

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