› › Structure analysis

ORC-O2-5: Human Origin Recognition Complex (ORC) with subunits 2,3,4,5

Electron Microscopy
3.5Å resolution
PDB entry 7jpq coloured by chain, front view.
PDB entry 7jpq coloured by chain, side view.
PDB entry 7jpq coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 4 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Origin recognition complex
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 77158.8 Å2
Buried surface area: 21357.99 Å2
Dissociation area: 3,688.7 Å2
Dissociation energy (ΔGdiss): 31.66 kcal/mol
Dissociation entropy (TΔSdiss): 16.49 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-129161

Macromolecules

Origin recognition complex subunit 2
Chain: B
Length: 577 amino acids
Theoretical weight: 66.06 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q13416 (Residues: 1-577; Coverage: 100%)
Gene names: ORC2, ORC2L
Pfam: Origin recognition complex subunit 2
InterPro: Origin recognition complex, subunit 2
Origin recognition complex subunit 2 in PDB entry 7jpq, assembly 1, front view.
Origin recognition complex subunit 2 in PDB entry 7jpq, assembly 1, side view.
Origin recognition complex subunit 2 in PDB entry 7jpq, assembly 1, top view.
Molecule details ›

Search similar proteins

Origin recognition complex subunit 3
Chain: C
Length: 712 amino acids
Theoretical weight: 82.44 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UBD5 (Residues: 1-505, 506-711; Coverage: 100%)
Gene names: LATHEO, ORC3, ORC3L
Pfam:
InterPro:
Origin recognition complex subunit 3 in PDB entry 7jpq, assembly 1, front view.
Origin recognition complex subunit 3 in PDB entry 7jpq, assembly 1, side view.
Origin recognition complex subunit 3 in PDB entry 7jpq, assembly 1, top view.
Molecule details ›

Search similar proteins

Origin recognition complex subunit 4
Chain: D
Length: 436 amino acids
Theoretical weight: 50.44 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O43929 (Residues: 1-436; Coverage: 100%)
Gene names: ORC4, ORC4L
Pfam:
InterPro:
Origin recognition complex subunit 4 in PDB entry 7jpq, assembly 1, front view.
Origin recognition complex subunit 4 in PDB entry 7jpq, assembly 1, side view.
Origin recognition complex subunit 4 in PDB entry 7jpq, assembly 1, top view.
Molecule details ›

Search similar proteins

Origin recognition complex subunit 5
Chain: E
Length: 435 amino acids
Theoretical weight: 50.35 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O43913 (Residues: 1-435; Coverage: 100%)
Gene names: ORC5, ORC5L
Pfam:
InterPro:
Origin recognition complex subunit 5 in PDB entry 7jpq, assembly 1, front view.
Origin recognition complex subunit 5 in PDB entry 7jpq, assembly 1, side view.
Origin recognition complex subunit 5 in PDB entry 7jpq, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links