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C-type carbohydrate-recognition domain 4 of the mannose receptor complexed with Man-alpha1-6Man

X-ray diffraction
1.4Å resolution
PDB entry 7jug coloured by chain, front view.
PDB entry 7jug coloured by chain, side view.
PDB entry 7jug coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Macrophage mannose receptor 1
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Multimeric state: monomeric
Accessible surface area: 7508.08 Å2
Buried surface area: 369.91 Å2
Dissociation area: 153.75 Å2
Dissociation energy (ΔGdiss): 3.08 kcal/mol
Dissociation entropy (TΔSdiss): 2.51 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149836

Macromolecules

Macrophage mannose receptor 1
Chain: A
Length: 135 amino acids
Theoretical weight: 15.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22897 (Residues: 646-779; Coverage: 9%)
Gene names: CLEC13D, CLEC13DL, MRC1, MRC1L1
Pfam: Lectin C-type domain
InterPro:
Macrophage mannose receptor 1 in PDB entry 7jug, assembly 1, front view.
Macrophage mannose receptor 1 in PDB entry 7jug, assembly 1, side view.
Macrophage mannose receptor 1 in PDB entry 7jug, assembly 1, top view.
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