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Succinate: quinone oxidoreductase SQR from E.coli K12

Source organism: Escherichia coli K-12
Biochemical function: electron transfer activity
Biological process: tricarboxylic acid cycle
Cellular component: membrane

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EC 1.3.5.1: Succinate dehydrogenase (quinone)

Reaction catalysed:
Succinate + a quinone = fumarate + a quinol
Systematic name:
Succinate:quinone oxidoreductase
Alternative Name(s):
  • Complex II
  • SDH
  • Succinate dehydrogenase (ubiquinone)
  • Succinate dehydrogenase complex
  • Succinate:ubiquinone oxidoreductase
  • Succinic dehydrogenase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01127
Domain description: Succinate dehydrogenase/Fumarate reductase transmembrane subunit
Occurring in:
  1. Succinate dehydrogenase cytochrome b556 subunit
The deposited structure of PDB entry 7jz2 contains 3 copies of Pfam domain PF01127 (Succinate dehydrogenase/Fumarate reductase transmembrane subunit) in Succinate dehydrogenase cytochrome b556 subunit. Showing 1 copy in chain C.

PF13534
Domain description: 4Fe-4S dicluster domain
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
The deposited structure of PDB entry 7jz2 contains 3 copies of Pfam domain PF13534 (4Fe-4S dicluster domain) in Succinate dehydrogenase iron-sulfur subunit. Showing 1 copy in chain B.

PF13085
Domain description: 2Fe-2S iron-sulfur cluster binding domain
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
The deposited structure of PDB entry 7jz2 contains 3 copies of Pfam domain PF13085 (2Fe-2S iron-sulfur cluster binding domain) in Succinate dehydrogenase iron-sulfur subunit. Showing 1 copy in chain B.

PF02910
Domain description: Fumarate reductase flavoprotein C-term
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
The deposited structure of PDB entry 7jz2 contains 3 copies of Pfam domain PF02910 (Fumarate reductase flavoprotein C-term) in Succinate dehydrogenase flavoprotein subunit. Showing 1 copy in chain A.

PF00890
Domain description: FAD binding domain
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
The deposited structure of PDB entry 7jz2 contains 3 copies of Pfam domain PF00890 (FAD binding domain) in Succinate dehydrogenase flavoprotein subunit. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR034804
Domain description: Fumarate reductase/succinate dehydrogenase, transmembrane subunit
Occurring in:
  1. Succinate dehydrogenase cytochrome b556 subunit
  2. Succinate dehydrogenase hydrophobic membrane anchor subunit
IPR014314
Domain description: Succinate dehydrogenase, cytochrome b556 subunit
Occurring in:
  1. Succinate dehydrogenase cytochrome b556 subunit
IPR014312
Domain description: Succinate dehydrogenase, hydrophobic membrane anchor
Occurring in:
  1. Succinate dehydrogenase hydrophobic membrane anchor subunit
IPR018495
Domain description: Succinate dehydrogenase, cytochrome b subunit, conserved site
Occurring in:
  1. Succinate dehydrogenase cytochrome b556 subunit
IPR001041
Domain description: 2Fe-2S ferredoxin-type iron-sulfur binding domain
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR027477
Domain description: Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR036188
Domain description: FAD/NAD(P)-binding domain superfamily
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR000701
Domain description: Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit
Occurring in:
  1. Succinate dehydrogenase cytochrome b556 subunit
IPR017900
Domain description: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR017896
Domain description: 4Fe-4S ferredoxin-type, iron-sulphur binding domain
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR009051
Domain description: Alpha-helical ferredoxin
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR004489
Domain description: Succinate dehydrogenase/fumarate reductase iron-sulphur protein
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR025192
Domain description: Succinate dehydogenase/fumarate reductase N-terminal
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR036010
Domain description: 2Fe-2S ferredoxin-like superfamily
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR012675
Domain description: Beta-grasp domain superfamily
Occurring in:
  1. Succinate dehydrogenase iron-sulfur subunit
IPR015939
Domain description: Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR037099
Domain description: Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR003952
Domain description: Fumarate reductase/succinate dehydrogenase, FAD-binding site
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR014006
Domain description: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR003953
Domain description: FAD-dependent oxidoreductase 2, FAD binding domain
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR030664
Domain description: FAD-dependent oxidoreductase SdhA/FrdA/AprA
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit
IPR011281
Domain description: Succinate dehydrogenase, flavoprotein subunit
Occurring in:
  1. Succinate dehydrogenase flavoprotein subunit

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