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Re-refined crystal structure of DNA-dependent protein kinase catalytic subunit complexed with Ku80 C-terminal helix

Source organism: Homo sapiens
Biochemical function: kinase activity
Biological process: double-strand break repair via nonhomologous end joining
Cellular component: nucleus

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF08785
Domain description: Ku C terminal domain like
Occurring in:
  1. X-ray repair cross-complementing protein 5
The deposited structure of PDB entry 7k17 contains 2 copies of Pfam domain PF08785 (Ku C terminal domain like) in X-ray repair cross-complementing protein 5. Showing 1 copy in chain D [auth C] (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR000403
Domain description: Phosphatidylinositol 3-/4-kinase, catalytic domain
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR036494
Domain description: Ku, C-terminal domain superfamily
Occurring in:
  1. X-ray repair cross-complementing protein 5
IPR003152
Domain description: FATC domain
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR018936
Domain description: Phosphatidylinositol 3/4-kinase, conserved site
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR045581
Domain description: DNA-dependent protein kinase catalytic subunit, CC5
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR012582
Domain description: DNA-dependent protein kinase catalytic subunit, CC3
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR014893
Domain description: Ku, C-terminal
Occurring in:
  1. X-ray repair cross-complementing protein 5
IPR036940
Domain description: Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR037706
Domain description: DNA-dependent protein kinase catalytic subunit, catalytic domain
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR011009
Domain description: Protein kinase-like domain superfamily
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR003151
Domain description: PIK-related kinase, FAT
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR014009
Domain description: PIK-related kinase
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR046803
Domain description: DNA-dependent protein kinase catalytic subunit, CC1/2
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR046804
Domain description: DNA-PKcs, N-terminal
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. DNA-dependent protein kinase catalytic subunit

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