Function and Biology

HCMV prefusion gB in complex with fusion inhibitor WAY-174865

Source organism: Human herpesvirus 5 strain Towne
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00606
Domain description: Herpesvirus Glycoprotein B ectodomain
Occurring in:
  1. Envelope glycoprotein B
The deposited structure of PDB entry 7kdp contains 3 copies of Pfam domain PF00606 (Herpesvirus Glycoprotein B ectodomain) in Envelope glycoprotein B. Showing 1 copy in chain A.

PF17417
Domain description: Herpesvirus Glycoprotein B PH-like domain
Occurring in:
  1. Envelope glycoprotein B
The deposited structure of PDB entry 7kdp contains 3 copies of Pfam domain PF17417 (Herpesvirus Glycoprotein B PH-like domain) in Envelope glycoprotein B. Showing 1 copy in chain A.

PF17416
Domain description: Herpesvirus Glycoprotein B
Occurring in:
  1. Envelope glycoprotein B
The deposited structure of PDB entry 7kdp contains 3 copies of Pfam domain PF17416 (Herpesvirus Glycoprotein B) in Envelope glycoprotein B. Showing 1 copy in chain A.

PF12154
Domain description: Glycoprotein B N-terminal antigenic domain of HCMV
Occurring in:
  1. Envelope glycoprotein B
The deposited structure of PDB entry 7kdp contains 3 copies of Pfam domain PF12154 (Glycoprotein B N-terminal antigenic domain of HCMV) in Envelope glycoprotein B. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR038631
Domain description: Herpesvirus Glycoprotein B, PH-like domain 2 superfamily
Occurring in:
  1. Envelope glycoprotein B
IPR035381
Domain description: Herpesvirus Glycoprotein B, PH-like domain 2
Occurring in:
  1. Envelope glycoprotein B
IPR035377
Domain description: Herpesvirus Glycoprotein B, PH-like domain 1
Occurring in:
  1. Envelope glycoprotein B
IPR021044
Domain description: Herpesvirus Glycoprotein B, antigenic domain, N-terminal
Occurring in:
  1. Envelope glycoprotein B
IPR000234
Domain description: Herpesvirus Glycoprotein B
Occurring in:
  1. Envelope glycoprotein B