Function and Biology

Outer dynein arm bound to doublet microtubules from C. reinhardtii

Source organism: Chlamydomonas reinhardtii
Biochemical function: metal ion binding
Biological process: microtubule-based process
Cellular component: cytoplasm

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF03953
Domain description: Tubulin C-terminal domain
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
The deposited structure of PDB entry 7kzm contains 8 copies of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin beta-1/beta-2 chain. Showing 1 copy in chain A [auth A1].
The deposited structure of PDB entry 7kzm contains 6 copies of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin alpha-1 chain. Showing 1 copy in chain B [auth A2].

PF00091
Domain description: Tubulin/FtsZ family, GTPase domain
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
The deposited structure of PDB entry 7kzm contains 8 copies of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin beta-1/beta-2 chain. Showing 1 copy in chain A [auth A1].
The deposited structure of PDB entry 7kzm contains 6 copies of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin alpha-1 chain. Showing 1 copy in chain B [auth A2].

PF13418
Domain description: Galactose oxidase, central domain
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
The deposited structure of PDB entry 7kzm contains 4 copies of Pfam domain PF13418 (Galactose oxidase, central domain) in PLD phosphodiesterase domain-containing protein. Showing 4 copies in chain O [auth A] (some of the copies are out of the observed residue ranges!).

PF03028
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03028 (Dynein heavy chain region D6 P-loop domain ) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03028 (Dynein heavy chain region D6 P-loop domain ) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03028 (Dynein heavy chain region D6 P-loop domain ) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF12777
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12777 (Microtubule-binding stalk of dynein motor) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12777 (Microtubule-binding stalk of dynein motor) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12777 (Microtubule-binding stalk of dynein motor) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF12780
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12780 (P-loop containing dynein motor region D4) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12780 (P-loop containing dynein motor region D4) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12780 (P-loop containing dynein motor region D4) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF12774
Domain description: Hydrolytic ATP binding site of dynein motor region
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12774 (Hydrolytic ATP binding site of dynein motor region) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12774 (Hydrolytic ATP binding site of dynein motor region) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF12774 (Hydrolytic ATP binding site of dynein motor region) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF08393
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF08393 (Dynein heavy chain, N-terminal region 2) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF08393 (Dynein heavy chain, N-terminal region 2) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF08393 (Dynein heavy chain, N-terminal region 2) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF21773
Domain description: ODAD1 central coiled coil region
Occurring in:
  1. Outer dynein arm protein 1
The deposited structure of PDB entry 7kzm contains 2 copies of Pfam domain PF21773 (Domain of unknown function (DUF6872)) in Outer dynein arm protein 1. Showing 1 copy in chain JA [auth Y1].

PF03259
Domain description: Roadblock/LC7 domain
Occurring in:
  1. Dynein light chain roadblock
  2. Dynein light chain roadblock
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03259 (Roadblock/LC7 domain) in Dynein light chain roadblock. Showing 1 copy in chain W [auth I].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03259 (Roadblock/LC7 domain) in Dynein light chain roadblock. Showing 1 copy in chain X [auth J].

PF03645
Domain description: Tctex-1 family
Occurring in:
  1. Mr19,000 outer arm dynein light chain
  2. Dynein light chain 9
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03645 (Tctex-1 family) in Mr19,000 outer arm dynein light chain. Showing 1 copy in chain T [auth F].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF03645 (Tctex-1 family) in Dynein light chain 9. Showing 1 copy in chain CA [auth O].

PF08385
Domain description: Dynein heavy chain, N-terminal region 1
Occurring in:
  1. Flagellar outer dynein arm heavy chain beta
  2. Dynein gamma chain, flagellar outer arm
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF08385 (Dynein heavy chain, N-terminal region 1) in Flagellar outer dynein arm heavy chain beta. Showing 1 copy in chain P [auth B].
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF08385 (Dynein heavy chain, N-terminal region 1) in Dynein gamma chain, flagellar outer arm. Showing 1 copy in chain Q [auth C].

PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Dynein 18 kDa light chain, flagellar outer arm
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF13499 (EF-hand domain pair) in Dynein 18 kDa light chain, flagellar outer arm. Showing 1 copy in chain U [auth G].

PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Dynein, 78 kDa intermediate chain, flagellar outer arm
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF00400 (WD domain, G-beta repeat) in Dynein, 78 kDa intermediate chain, flagellar outer arm. Showing 1 copy in chain R [auth D].

PF00630
Domain description: Filamin/ABP280 repeat
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF00630 (Filamin/ABP280 repeat) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A] (this domain is out of the observed residue ranges!).

PF01833
Domain description: IPT/TIG domain
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF01833 (IPT/TIG domain) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A] (this domain is out of the observed residue ranges!).

PF07646
Domain description: Kelch motif
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
The deposited structure of PDB entry 7kzm contains 1 copy of Pfam domain PF07646 (Kelch motif) in PLD phosphodiesterase domain-containing protein. Showing 1 copy in chain O [auth A].

InterPro InterPro annotations
IPR000217
Domain description: Tubulin
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR002453
Domain description: Beta tubulin
Occurring in:
  1. Tubulin beta-1/beta-2 chain
IPR002452
Domain description: Alpha tubulin
Occurring in:
  1. Tubulin alpha-1 chain
IPR018316
Domain description: Tubulin/FtsZ, 2-layer sandwich domain
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR003008
Domain description: Tubulin/FtsZ, GTPase domain
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR036525
Domain description: Tubulin/FtsZ, GTPase domain superfamily
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
IPR001372
IPR002048
IPR023123
Domain description: Tubulin, C-terminal
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR037103
Domain description: Tubulin/FtsZ-like, C-terminal domain
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR008280
Domain description: Tubulin/FtsZ, C-terminal
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR017975
Domain description: Tubulin, conserved site
Occurring in:
  1. Tubulin beta-1/beta-2 chain
  2. Tubulin alpha-1 chain
IPR037177
IPR013838
Domain description: Beta tubulin, autoregulation binding site
Occurring in:
  1. Tubulin beta-1/beta-2 chain
IPR003593
IPR015915
Domain description: Kelch-type beta propeller
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR019763
Domain description: Dynein light chain, type 1/2, conserved site
Occurring in:
  1. Dynein 11 kDa light chain, flagellar outer arm
  2. Dynein 8 kDa light chain, flagellar outer arm
IPR004942
Domain description: Roadblock/LAMTOR2 domain
Occurring in:
  1. Dynein light chain roadblock
  2. Dynein light chain roadblock
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Dynein 18 kDa light chain, flagellar outer arm
  2. EF-hand domain-containing protein
IPR005334
Domain description: Dynein light chain Tctex-1 like
Occurring in:
  1. Mr19,000 outer arm dynein light chain
  2. Dynein light chain 9
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Dynein, 78 kDa intermediate chain, flagellar outer arm
  2. Dynein, 70 kDa intermediate chain, flagellar outer arm
IPR043160
Domain description: Dynein heavy chain, C-terminal domain, barrel region
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
IPR041228
IPR042219
IPR004273
IPR035706
Domain description: Dynein heavy chain, ATP-binding dynein motor region
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
IPR024743
IPR041589
IPR041466
IPR043157
Domain description: Dynein heavy chain, AAA1 domain, small subdomain
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
IPR035699
Domain description: Dynein heavy chain, hydrolytic ATP-binding dynein motor region
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
  2. Flagellar outer dynein arm heavy chain beta
  3. Dynein gamma chain, flagellar outer arm
IPR042228
IPR042222
IPR016561
Domain description: Dynein light chain roadblock-type 1/2
Occurring in:
  1. Dynein light chain roadblock
  2. Dynein light chain roadblock
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Dynein 18 kDa light chain, flagellar outer arm
  2. EF-hand domain-containing protein
IPR038586
Domain description: Tctex-1-like superfamily
Occurring in:
  1. Mr19,000 outer arm dynein light chain
  2. Dynein light chain 9
IPR036322
Domain description: WD40-repeat-containing domain superfamily
Occurring in:
  1. Dynein, 78 kDa intermediate chain, flagellar outer arm
  2. Dynein, 70 kDa intermediate chain, flagellar outer arm
IPR013594
Domain description: Dynein heavy chain, tail
Occurring in:
  1. Flagellar outer dynein arm heavy chain beta
  2. Dynein gamma chain, flagellar outer arm
IPR017868
Domain description: Filamin/ABP280 repeat-like
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR014756
Domain description: Immunoglobulin E-set
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR001736
Domain description: Phospholipase D/Transphosphatidylase
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR011043
Domain description: Galactose oxidase/kelch, beta-propeller
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR001298
Domain description: Filamin/ABP280 repeat
Occurring in:
  1. PLD phosphodiesterase domain-containing protein
IPR002909
Domain description: IPT domain
Occurring in:
  1. PLD phosphodiesterase domain-containing protein