Structure analysis

cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-bound state

Electron Microscopy
2.71Å resolution
Source organism: Rattus norvegicus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 117856.72 Å2
Buried surface area: 24093.94 Å2
Dissociation area: 12,046.97 Å2
Dissociation energy (ΔGdiss): 214.64 kcal/mol
Dissociation entropy (TΔSdiss): 49.75 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-128685

Macromolecules

Chains: A, B, C, D
Length: 637 amino acids
Theoretical weight: 73.02 KDa
Source organism: Rattus norvegicus
Expression system: Homo sapiens
UniProt:
  • Canonical: O35433 (Residues: 110-764; Coverage: 75%)
Gene names: Trpv1, Vr1, Vr1l
Pfam:
InterPro:

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