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E. coli MsbA in complex with G247

Electron Microscopy
3.9Å resolution
PDB entry 7mew coloured by chain, front view.
PDB entry 7mew coloured by chain, side view.
PDB entry 7mew coloured by chain, top view.
Source organism: Escherichia coli
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA
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Multimeric state: homo dimer
Accessible surface area: 62389.29 Å2
Buried surface area: 8220.79 Å2
Dissociation area: 4,110.4 Å2
Dissociation energy (ΔGdiss): 71.77 kcal/mol
Dissociation entropy (TΔSdiss): 16.17 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-102945

Macromolecules

Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA
Chains: A, B
Length: 605 amino acids
Theoretical weight: 67.31 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A140NBS6 (Residues: 1-582; Coverage: 100%)
Gene name: ECBD_2681
Pfam:
InterPro:
Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA in PDB entry 7mew, assembly 1, front view.
Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA in PDB entry 7mew, assembly 1, side view.
Lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA in PDB entry 7mew, assembly 1, top view.
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