› › Function and Biology

Crystal structure of Paradendryphiella salina PL7A alginate lyase mutant Y223F in complex with hexa-mannuronic acid

Source organism: Paradendryphiella salina
Biochemical function: lyase activity
Biological process: not assigned
Cellular component: not assigned

Quick links

EC 4.2.2.3: Mannuronate-specific alginate lyase

Reaction catalysed:
Eliminative cleavage of alginate to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends and beta-D-mannuronate at their reducing end.
Systematic name:
Alginate beta-D-mannuronate--uronate lyase
Alternative Name(s):
  • Alginase
  • Alginase I
  • Alginase II
  • Alginate lyase
  • Alginate lyase I
  • Aly (gene name)
  • Poly((1->4)-beta-D-mannuronide) lyase
  • Poly(beta-D-1,4-mannuronide) lyase
  • Poly(beta-D-mannuronate) lyase
  • Poly(mana) alginate lyase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF08787
Domain description: Alginate lyase
Occurring in:
  1. Alginate lyase 2 domain-containing protein
The deposited structure of PDB entry 7ncz contains 1 copy of Pfam domain PF08787 (Alginate lyase) in Alginate lyase 2 domain-containing protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013320
Domain description: Concanavalin A-like lectin/glucanase domain superfamily
Occurring in:
  1. Alginate lyase 2 domain-containing protein
IPR014895
Domain description: Alginate lyase 2
Occurring in:
  1. Alginate lyase 2 domain-containing protein

Quick links