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Structure of the fungal plasma membrane proton pump Pma1 in its auto-inhibited state - monomer unit

Source organism: Neurospora crassa
Biochemical function: metal ion binding
Biological process: proton transmembrane transport
Cellular component: membrane

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EC 7.1.2.1: P-type H(+)-exporting transporter

Reaction catalysed:
ATP + H(2)O + H(+)(Side 1) = ADP + phosphate + H(+)(Side 2)
Systematic name:
ATP phosphohydrolase (P-type, H(+)-exporting)
Alternative Name(s):
  • ATP phosphohydrolase
  • H(+)-transporting ATPase
  • Proton transport ATPase
  • Proton-translocating ATPase
  • Proton-translocating P-type ATPase
  • Yeast plasma membrane ATPase
  • Yeast plasma membrane H(+)-ATPase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00702
Domain description: haloacid dehalogenase-like hydrolase
Occurring in:
  1. Plasma membrane ATPase
The deposited structure of PDB entry 7nxf contains 1 copy of Pfam domain PF00702 (haloacid dehalogenase-like hydrolase) in Plasma membrane ATPase. Showing 1 copy in chain A.

PF00122
Domain description: E1-E2 ATPase
Occurring in:
  1. Plasma membrane ATPase
The deposited structure of PDB entry 7nxf contains 1 copy of Pfam domain PF00122 (E1-E2 ATPase) in Plasma membrane ATPase. Showing 1 copy in chain A.

PF00690
Domain description: Cation transporter/ATPase, N-terminus
Occurring in:
  1. Plasma membrane ATPase
The deposited structure of PDB entry 7nxf contains 1 copy of Pfam domain PF00690 (Cation transporter/ATPase, N-terminus) in Plasma membrane ATPase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001757
Domain description: P-type ATPase
Occurring in:
  1. Plasma membrane ATPase
IPR006534
Domain description: P-type ATPase, subfamily IIIA
Occurring in:
  1. Plasma membrane ATPase
IPR004014
Domain description: Cation-transporting P-type ATPase, N-terminal
Occurring in:
  1. Plasma membrane ATPase
IPR023299
Domain description: P-type ATPase, cytoplasmic domain N
Occurring in:
  1. Plasma membrane ATPase
IPR018303
Domain description: P-type ATPase, phosphorylation site
Occurring in:
  1. Plasma membrane ATPase
IPR036412
Domain description: HAD-like superfamily
Occurring in:
  1. Plasma membrane ATPase
IPR023214
Domain description: HAD superfamily
Occurring in:
  1. Plasma membrane ATPase
IPR044492
Domain description: P-type ATPase, haloacid dehalogenase domain
Occurring in:
  1. Plasma membrane ATPase
IPR008250
Domain description: P-type ATPase, A domain superfamily
Occurring in:
  1. Plasma membrane ATPase
IPR023298
Domain description: P-type ATPase, transmembrane domain superfamily
Occurring in:
  1. Plasma membrane ATPase

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