EC 2.7.1.153: Phosphatidylinositol-4,5-bisphosphate 3-kinase
Reaction catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate
Systematic name:
ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase
Alternative Name(s):
- Type I phosphoinositide 3-kinase
EC 2.7.1.137: Phosphatidylinositol 3-kinase
Reaction catalysed:
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate
Systematic name:
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase
Alternative Name(s):
- 1-phosphatidylinositol 3-kinase
- PI3-kinase
- PtdIns-3-kinase
- Type I phosphatidylinositol kinase
- Type III phosphoinositide 3-kinase
- Vps34p
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
PF00613
Domain description:
Phosphoinositide 3-kinase family, accessory domain (PIK domain)
Occurring in:
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>7oil</span> contains 1 copy of Pfam domain <span class='highlight'>PF00613 (Phosphoinositide 3-kinase family, accessory domain (PIK domain))</span> in <span class='highlight'>Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform</span>. Showing 1 copy in chain <span class='highlight'>A [auth AAA]</span>. The deposited structure of PDB entry 7oil contains 1 copy of Pfam domain PF00613 (Phosphoinositide 3-kinase family, accessory domain (PIK domain)) in Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform. Showing 1 copy in chain A [auth AAA].](https://www.ebi.ac.uk/pdbe/static/entry/7oil_1_AAA_Pfam_PF00613_image-200x200.png)
InterPro annotations
IPR000341
Domain description:
Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain
Occurring in:
Occurring in: