EC 2.7.7.102: DNA primase AEP
Reaction catalysed:
SsDNA + n NTP = ssDNA/pppN(pN)(n-1) hybrid + (n-1) diphosphate
Systematic name:
(Deoxy)nucleotide 5'-triphosphate:single-stranded DNA (deoxy)nucleotidyltransferase (DNA or DNA-RNA hybrid synthesizing)
Alternative Name(s):
- AEP
- Archaeo-eukaryotic primase
- PrimPol
EC 3.4.22.69: SARS coronavirus main proteinase
Reaction catalysed:
TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
Systematic name:
-
Alternative Name(s):
- 3C-like protease
- 3cLpro
- Coronavirus 3C-like protease
- Mpro
- SARS 3C-like protease
- SARS coronavirus 3CL protease
- SARS coronavirus main peptidase
- SARS coronavirus main protease
- SARS-CoV 3CLpro enzyme
- SARS-CoV Mpro
- SARS-CoV main protease
- Severe acute respiratory syndrome coronavirus main protease
EC 3.4.19.12: Ubiquitinyl hydrolase 1
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
- Ubiquitin C-terminal hydrolase
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin thiolesterase
- Yeast ubiquitin hydrolase
EC 2.7.7.50: mRNA guanylyltransferase
Reaction catalysed:
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Systematic name:
GTP:mRNA guanylyltransferase
Alternative Name(s):
- GTP--RNA guanylyltransferase
- Messenger RNA guanylyltransferase
- Protein lambda-2
- mRNA capping enzyme
EC 2.7.7.7: DNA-directed DNA polymerase
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Systematic name:
Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Alternative Name(s):
- DNA duplicase
- DNA nucleotidyltransferase
- DNA nucleotidyltransferase (DNA-directed)
- DNA polymerase
- DNA polymerase I
- DNA polymerase II
- DNA polymerase III
- DNA polymerase alpha
- DNA polymerase beta
- DNA polymerase gamma
- DNA replicase
- DNA-dependent DNA polymerase
- Deoxynucleate polymerase
- Deoxyribonucleate nucleotidyltransferase
- Deoxyribonucleic acid duplicase
- Deoxyribonucleic acid polymerase
- Deoxyribonucleic duplicase
- Deoxyribonucleic polymerase
- Deoxyribonucleic polymerase I
- Duplicase
- Klenow fragment
- Sequenase
- Taq DNA polymerase
- Taq Pol I
- Tca DNA polymerase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR015088
Domain description:
Zinc finger, DNA-directed DNA polymerase, family B, alpha
Occurring in:
Occurring in:
IPR045846
Domain description:
DNA polymerase alpha catalytic subunit, catalytic domain
Occurring in:
Occurring in:
IPR006134
Domain description:
DNA-directed DNA polymerase, family B, multifunctional domain
Occurring in:
Occurring in: