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The crystal structure of the domain-swapped dimer of onconase

X-ray diffraction
2.12Å resolution
PDB entry 7or6 coloured by chain, front view.
PDB entry 7or6 coloured by chain, side view.
PDB entry 7or6 coloured by chain, top view.
Source organism: Lithobates pipiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein P-30
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Multimeric state: homo dimer
Accessible surface area: 11038.64 Å2
Buried surface area: 3461.5 Å2
Dissociation area: 1,730.75 Å2
Dissociation energy (ΔGdiss): 14.33 kcal/mol
Dissociation entropy (TΔSdiss): 11.4 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-149515

Macromolecules

Protein P-30
Chains: AAA, BBB
Length: 105 amino acids
Theoretical weight: 11.97 KDa
Source organism: Lithobates pipiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P22069 (Residues: 2-104; Coverage: 99%)
Pfam: Pancreatic ribonuclease
InterPro:
Protein P-30 in PDB entry 7or6, assembly 1, front view.
Protein P-30 in PDB entry 7or6, assembly 1, side view.
Protein P-30 in PDB entry 7or6, assembly 1, top view.
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