7ow7

Electron Microscopy
2.4Å resolution

EIF6-bound large subunit of the human ribosome

Released:
Source organism: Homo sapiens
Entry authors: Faille A, Warren AJ
Related structures: EMD-13094

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 43-mer (preferred)
PDBe Complex ID:
PDB-CPX-250225 (preferred)
Entry contents:
40 distinct polypeptide molecules
3 distinct RNA molecules
Macromolecules (43 distinct):
Large ribosomal subunit protein uL2 Chain: D
Molecule details ›
Chain: D
Length: 257 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62917 (Residues: 1-257; Coverage: 100%)
Gene name: RPL8
Sequence domains:
60S ribosomal protein L3 isoform a Chain: E
Molecule details ›
Chain: E
Length: 430 amino acids
Theoretical weight: 48.92 KDa
Source organism: Homo sapiens
Large ribosomal subunit protein uL4 Chain: F
Large ribosomal subunit protein uL18 Chain: G
Large ribosomal subunit protein eL6 Chain: H
Large ribosomal subunit protein uL30 Chain: m
Large ribosomal subunit protein eL8 Chain: n
Large ribosomal subunit protein uL6 Chain: o
Ribosomal protein uL16-like Chain: p
Large ribosomal subunit protein uL5 Chain: q
Large ribosomal subunit protein eL13 Chain: r
Large ribosomal subunit protein eL14 Chain: s
Large ribosomal subunit protein eL15 Chain: t
Large ribosomal subunit protein uL13 Chain: I
Large ribosomal subunit protein uL22 Chain: J
Large ribosomal subunit protein eL18 Chain: K
Large ribosomal subunit protein eL19 Chain: L
Large ribosomal subunit protein eL20 Chain: M
Large ribosomal subunit protein eL21 Chain: N
Large ribosomal subunit protein uL23 Chain: R
Large ribosomal subunit protein uL24 Chain: S
Large ribosomal subunit protein eL27 Chain: T
Large ribosomal subunit protein uL15 Chain: U
Large ribosomal subunit protein eL29 Chain: V
Large ribosomal subunit protein eL30 Chain: W
Large ribosomal subunit protein eL31 Chain: X
Large ribosomal subunit protein eL32 Chain: Y
Large ribosomal subunit protein eL33 Chain: Z
Large ribosomal subunit protein eL34 Chain: a
Large ribosomal subunit protein uL29 Chain: b
Large ribosomal subunit protein eL36 Chain: c
Large ribosomal subunit protein eL37 Chain: d
Large ribosomal subunit protein eL38 Chain: e
60S ribosomal protein L39 Chain: f
Large ribosomal subunit protein eL42 Chain: i
Large ribosomal subunit protein eL43 Chain: j
Large ribosomal subunit protein eL28 Chain: k
Eukaryotic translation initiation factor 6 Chain: P
Large ribosomal subunit protein uL14 Chain: Q
Large ribosomal subunit protein eL24 Chain: u
28S ribosomal RNA Chain: A
5S ribosomal RNA Chain: B
5.8S ribosomal RNA Chain: C

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
Resolution: 2.4Å
Relevant EMDB volumes: EMD-13094