7p7r

Electron Microscopy
2.9Å resolution

PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state I

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 53-mer (preferred)
PDBe Complex ID:
PDB-CPX-157827 (preferred)
Entry contents:
48 distinct polypeptide molecules
5 distinct RNA molecules
Macromolecules (53 distinct):
ARE-ABC-F family resistance factor PoxtA Chain: 0
Molecule details ›
Chain: 0
Length: 586 amino acids
Theoretical weight: 67.89 KDa
Source organism: Enterococcus faecalis V583
Expression system: Enterococcus faecalis
Large ribosomal subunit protein uL29 Chain: 1
Molecule details ›
Chain: 1
Length: 62 amino acids
Theoretical weight: 7.34 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL30 Chain: 2
Molecule details ›
Chain: 2
Length: 59 amino acids
Theoretical weight: 6.37 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL31B Chain: 3
Molecule details ›
Chain: 3
Length: 89 amino acids
Theoretical weight: 10.14 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL32C Chain: 4
Molecule details ›
Chain: 4
Length: 59 amino acids
Theoretical weight: 6.5 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL33C Chain: 5
Molecule details ›
Chain: 5
Length: 48 amino acids
Theoretical weight: 5.92 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL34 Chain: 6
Molecule details ›
Chain: 6
Length: 44 amino acids
Theoretical weight: 5.37 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL35 Chain: 7
Molecule details ›
Chain: 7
Length: 65 amino acids
Theoretical weight: 7.6 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL36 Chain: 8
Molecule details ›
Chain: 8
Length: 38 amino acids
Theoretical weight: 4.44 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL1 Chain: F
Molecule details ›
Chain: F
Length: 229 amino acids
Theoretical weight: 24.5 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL2 Chain: G
Molecule details ›
Chain: G
Length: 276 amino acids
Theoretical weight: 30.29 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL3 Chain: H
Molecule details ›
Chain: H
Length: 209 amino acids
Theoretical weight: 22.76 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL4 Chain: I
Molecule details ›
Chain: I
Length: 207 amino acids
Theoretical weight: 22.55 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL5 Chain: J
Molecule details ›
Chain: J
Length: 179 amino acids
Theoretical weight: 20.12 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL6 Chain: K
Molecule details ›
Chain: K
Length: 178 amino acids
Theoretical weight: 19.44 KDa
Source organism: Enterococcus faecalis V583
50S ribosomal protein L13 Chain: M
Molecule details ›
Chain: M
Length: 147 amino acids
Theoretical weight: 16.33 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL14 Chain: N
Molecule details ›
Chain: N
Length: 122 amino acids
Theoretical weight: 13.17 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL15 Chain: O
Molecule details ›
Chain: O
Length: 146 amino acids
Theoretical weight: 15.6 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL16 Chain: P
Molecule details ›
Chain: P
Length: 144 amino acids
Theoretical weight: 16.22 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL17 Chain: Q
Molecule details ›
Chain: Q
Length: 127 amino acids
Theoretical weight: 14.5 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL18 Chain: R
Molecule details ›
Chain: R
Length: 118 amino acids
Theoretical weight: 12.94 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL19 Chain: S
Molecule details ›
Chain: S
Length: 115 amino acids
Theoretical weight: 13.24 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL20 Chain: T
Molecule details ›
Chain: T
Length: 119 amino acids
Theoretical weight: 13.67 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL21 Chain: U
Molecule details ›
Chain: U
Length: 102 amino acids
Theoretical weight: 11.17 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL22 Chain: V
Molecule details ›
Chain: V
Length: 115 amino acids
Theoretical weight: 12.47 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL23 Chain: W
Molecule details ›
Chain: W
Length: 96 amino acids
Theoretical weight: 11.09 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein uL24 Chain: X
Molecule details ›
Chain: X
Length: 103 amino acids
Theoretical weight: 11.11 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL27 Chain: Y
Molecule details ›
Chain: Y
Length: 95 amino acids
Theoretical weight: 10.18 KDa
Source organism: Enterococcus faecalis V583
Large ribosomal subunit protein bL28 Chain: Z
Molecule details ›
Chain: Z
Length: 62 amino acids
Theoretical weight: 7.01 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS2 Chain: c
Molecule details ›
Chain: c
Length: 261 amino acids
Theoretical weight: 29.5 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS3 Chain: d
Molecule details ›
Chain: d
Length: 218 amino acids
Theoretical weight: 24.42 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS4 Chain: e
Molecule details ›
Chain: e
Length: 203 amino acids
Theoretical weight: 23.27 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS5 Chain: f
Molecule details ›
Chain: f
Length: 166 amino acids
Theoretical weight: 17.44 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein bS6 Chain: g
Molecule details ›
Chain: g
Length: 99 amino acids
Theoretical weight: 11.55 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS7 Chain: h
Molecule details ›
Chain: h
Length: 156 amino acids
Theoretical weight: 17.86 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS8 Chain: i
Molecule details ›
Chain: i
Length: 132 amino acids
Theoretical weight: 14.94 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS9 Chain: j
Molecule details ›
Chain: j
Length: 130 amino acids
Theoretical weight: 14.27 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS10 Chain: k
Molecule details ›
Chain: k
Length: 102 amino acids
Theoretical weight: 11.73 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS11 Chain: l
Molecule details ›
Chain: l
Length: 129 amino acids
Theoretical weight: 13.74 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS12 Chain: m
Molecule details ›
Chain: m
Length: 137 amino acids
Theoretical weight: 15.31 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS13 Chain: n
Molecule details ›
Chain: n
Length: 121 amino acids
Theoretical weight: 13.6 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS14C Chain: o
Molecule details ›
Chain: o
Length: 61 amino acids
Theoretical weight: 7.17 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS15 Chain: p
Molecule details ›
Chain: p
Length: 89 amino acids
Theoretical weight: 10.67 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein bS16 Chain: q
Molecule details ›
Chain: q
Length: 91 amino acids
Theoretical weight: 10.36 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS17 Chain: r
Molecule details ›
Chain: r
Length: 88 amino acids
Theoretical weight: 10.33 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein bS18 Chain: s
Molecule details ›
Chain: s
Length: 79 amino acids
Theoretical weight: 9.26 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein uS19 Chain: t
Molecule details ›
Chain: t
Length: 92 amino acids
Theoretical weight: 10.59 KDa
Source organism: Enterococcus faecalis V583
Small ribosomal subunit protein bS20 Chain: u
Molecule details ›
Chain: u
Length: 83 amino acids
Theoretical weight: 8.97 KDa
Source organism: Enterococcus faecalis V583
23S ribosomal RNA Chain: A
Molecule details ›
Chain: A
Length: 2912 nucleotides
Theoretical weight: 944 KDa
Source organism: Enterococcus faecalis V583
Sequence domains: Bacterial large subunit ribosomal RNA
5S ribosomal RNA Chain: B
Molecule details ›
Chain: B
Length: 115 nucleotides
Theoretical weight: 37.13 KDa
Source organism: Enterococcus faecalis V583
Sequence domains: 5S ribosomal RNA
tRNA-fMet Chain: D
Molecule details ›
Chain: D
Length: 77 nucleotides
Theoretical weight: 24.81 KDa
Source organism: Enterococcus faecalis V583
Sequence domains: tRNA
16S ribosomal RNA Chain: a
Molecule details ›
Chain: a
Length: 1558 nucleotides
Theoretical weight: 504.22 KDa
Source organism: Enterococcus faecalis V583
Sequence domains: Bacterial small subunit ribosomal RNA
Messenger RNA Chain: b
Molecule details ›
Chain: b
Length: 19 nucleotides
Theoretical weight: 6.22 KDa
Source organism: Enterococcus faecalis V583

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.9Å
Relevant EMDB volumes: EMD-13242
Expression system: Enterococcus faecalis