Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero octamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134225 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Insulin receptor
Molecule details ›
Chains: A, B
Length: 1382 amino acids
Theoretical weight: 156.7 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt: Gene name: INSR
Sequence domains:
Length: 1382 amino acids
Theoretical weight: 156.7 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt: Gene name: INSR
Sequence domains:
Insulin A chain
Molecule details ›
Chains: C, E, I
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
Length: 21 amino acids
Theoretical weight: 2.38 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P01308 (Residues: 90-110; Coverage: 24%)
Insulin B chain
