Structure analysis

Crystal structure of human galectin-3 CRD in complex with selenodigalactoside

X-ray diffraction
1.96Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 7428.38 Å2
Buried surface area: 131.0 Å2
Dissociation area: 65.5 Å2
Dissociation energy (ΔGdiss): 10.05 kcal/mol
Dissociation entropy (TΔSdiss): -0.83 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-148215

Macromolecules

Chain: A
Length: 139 amino acids
Theoretical weight: 15.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17931 (Residues: 112-250; Coverage: 56%)
Gene names: LGALS3, MAC2
Pfam: Galactoside-binding lectin
InterPro:
PDBe-KB: UniProt Coverage View: P17931  
1139102030405060708090100110120130
 
50100
UniProt
P17931
Chains
Domains
Secondary structure
Ligand binding sites
Sequence conservation

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