Function and Biology Details
Reaction catalysed:
(1a) a 14-alpha-methylsteroid + [reduced NADPH--hemoprotein reductase] + O(2) = a 14-alpha-hydroxysteroid + [oxidized NADPH--hemoprotein reductase] + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Lanosterol 14-alpha demethylase CYP51 (preferred)
PDBe Complex ID:
PDB-CPX-145359 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lanosterol 14-alpha demethylase CYP51
Molecule details ›
Chain: A
Length: 539 amino acids
Theoretical weight: 61.87 KDa
Source organism: Saccharomyces cerevisiae YJM789
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Cytochrome P450
Length: 539 amino acids
Theoretical weight: 61.87 KDa
Source organism: Saccharomyces cerevisiae YJM789
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P10614 (Residues: 1-530; Coverage: 100%)
Sequence domains: Cytochrome P450
