GO terms
Biochemical function:
- transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
- ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
- ligand-gated monoatomic cation channel activity
- scaffold protein binding
- protein-containing complex binding
- identical protein binding
- signaling receptor activity
- ionotropic glutamate receptor binding
- glutamate receptor binding
- PDZ domain binding
- inorganic cation transmembrane transporter activity
- glutamate-gated calcium ion channel activity
- protein kinase binding
- immunoglobulin binding
- kainate selective glutamate receptor activity
- ligand-gated monoatomic ion channel activity
- cytoskeletal protein binding
- protein binding
- extracellularly glutamate-gated ion channel activity
- extracellular ligand-gated monoatomic ion channel activity
- AMPA glutamate receptor activity
- glutamate-gated receptor activity
- amyloid-beta binding
- SNARE binding
Biological process:
- cellular response to brain-derived neurotrophic factor stimulus
- cellular response to glycine
- regulation of presynaptic membrane potential
- monoatomic cation transmembrane transport
- response to fungicide
- excitatory postsynaptic potential
- regulation of postsynaptic membrane potential
- regulation of synaptic transmission, glutamatergic
- protein tetramerization
- positive regulation of synaptic transmission
- modulation of chemical synaptic transmission
- establishment of protein localization
- synaptic transmission, glutamatergic
- ionotropic glutamate receptor signaling pathway
- monoatomic ion transmembrane transport
- receptor internalization
- cerebral cortex development
- calcium-mediated signaling
- response to lithium ion
- chemical synaptic transmission
- calcium ion transport
- regulation of receptor recycling
Cellular component:
- spine synapse
- perisynaptic space
- glutamatergic synapse
- postsynaptic density membrane
- presynapse
- Schaffer collateral - CA1 synapse
- synaptic membrane
- presynaptic active zone membrane
- postsynaptic membrane
- synapse
- dendritic spine head
- dendritic spine neck
- organelle
- perikaryon
- dendritic shaft
- dendritic spine
- terminal bouton
- neuronal cell body
- neuron projection
- presynaptic membrane
- somatodendritic compartment
- protein-containing complex
- dendrite cytoplasm
- dendrite membrane
- AMPA glutamate receptor complex
- asymmetric synapse
- synaptic vesicle membrane
- growth cone
- dendrite
- axon
- membrane
- postsynaptic density
- cell surface
- ionotropic glutamate receptor complex
- synaptic vesicle
- plasma membrane
- endoplasmic reticulum
Sequence families
Protein families (Pfam)
InterPro annotations
IPR019594
Domain description:
Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
Occurring in:
Occurring in: