Structure analysis

Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK 200775

Electron Microscopy
3.6Å resolution
Source organism: Rattus norvegicus
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo tetramer
Accessible surface area: 171482.02 Å2
Buried surface area: 46472.88 Å2
Dissociation area: 7,167.43 Å2
Dissociation energy (ΔGdiss): 105.35 kcal/mol
Dissociation entropy (TΔSdiss): 19.67 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-148611

Macromolecules

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