Assemblies
Multimeric state:
hetero dimer
Accessible surface area:
56621.74 Å2
Buried surface area:
1070.61 Å2
Dissociation area:
535.31
Å2
Dissociation energy (ΔGdiss):
-3.45
kcal/mol
Dissociation entropy (TΔSdiss):
7.98
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-146649
Macromolecules
Chain: A
Length: 1480 amino acids
Theoretical weight: 168.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam:
Length: 1480 amino acids
Theoretical weight: 168.34 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P13569 (Residues: 1-1480; Coverage: 100%)
Pfam:
- ABC transporter transmembrane region
- ABC transporter
- Cystic fibrosis TM conductance regulator (CFTR), regulator domain
- Cystic fibrosis transmembrane conductance regulator
- ABC transporter type 1, transmembrane domain superfamily
- ABC transporter type 1, transmembrane domain
- P-loop containing nucleoside triphosphate hydrolase
- Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette domain 1
- ABC transporter-like, ATP-binding domain
- AAA+ ATPase domain
- ABC transporter-like, conserved site
- CFTR regulator domain
Chain: B
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens