› 7sww

Electron Microscopy
3.13Å resolution

SARS-CoV-2 Spike NTD in complex with neutralizing Fab SARS2-57 (local refinement)

Released:
DOI: 10.2210/pdb7sww/pdb
PDB entry 7sww coloured by chain, front view.
PDB entry 7sww coloured by chain, side view.
PDB entry 7sww coloured by chain, top view.
Source organisms:
Entry authors: Adams LJ, Fremont DH, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Structural Biology of Infectious Diseases (CSBID)
Related structures: EMD-25487

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-225195 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (4 distinct):
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 291 amino acids
Theoretical weight: 33.08 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 14-304; Coverage: 23%)
Gene names: 2, S
Sequence domains: Betacoronavirus-like spike glycoprotein S1, N-terminal
SARS2-57 Fv heavy chain Chain: H
Molecule details ›
Chain: H
Length: 117 amino acids
Theoretical weight: 12.96 KDa
Source organism: Mus musculus
SARS2-57 Fv light chain Chain: L
Molecule details ›
Chain: L
Length: 112 amino acids
Theoretical weight: 12.38 KDa
Source organism: Mus musculus

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Ligand NAG 4 x NAG
1 bound ligand:
Ligand NAG 4 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.13Å
Relevant EMDB volumes: EMD-25487
Expression system: Homo sapiens

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