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Reconstruction of full-length Prex-1 (PtdIns(3,4,5)P3-dependent Rac Exchanger 1)

Source organisms:
Biochemical function: hydrolase activity, acting on glycosyl bonds
Biological process: viral release from host cell by cytolysis
Cellular component: host cell cytoplasm

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EC 3.2.1.17: Lysozyme

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Systematic name:
Peptidoglycan N-acetylmuramoylhydrolase
Alternative Name(s):
  • 1,4-N-acetylmuramidase
  • Globulin G
  • Globulin G1
  • L-7001
  • Lysozyme g
  • Mucopeptide N-acetylmuramoylhydrolase
  • Mucopeptide glucohydrolase
  • Muramidase
  • N,O-diacetylmuramidase
  • PR1-lysozyme

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00610
Domain description: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
The deposited structure of PDB entry 7syf contains 2 copies of Pfam domain PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)) in Endolysin. Showing 2 copies in chain A.

PF00959
Domain description: Phage lysozyme
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
The deposited structure of PDB entry 7syf contains 1 copy of Pfam domain PF00959 (Phage lysozyme) in Endolysin. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF22697
Domain description: SOS1/NGEF-like PH domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

PF00621
Domain description: RhoGEF domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
The deposited structure of PDB entry 7syf contains 1 copy of Pfam domain PF00621 (RhoGEF domain) in Endolysin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001165
Domain description: T4-type lysozyme
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR000591
Domain description: DEP domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR036034
Domain description: PDZ superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR000219
Domain description: Dbl homology (DH) domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR001478
Domain description: PDZ domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR035899
Domain description: Dbl homology (DH) domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR023347
Domain description: Lysozyme domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR002196
Domain description: Glycoside hydrolase, family 24
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR023346
Domain description: Lysozyme-like domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR034690
Domain description: Endolysin T4 type
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR001849
Domain description: Pleckstrin homology domain
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR011993
Domain description: PH-like domain superfamily
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein
IPR001331
Domain description: Guanine-nucleotide dissociation stimulator, CDC24, conserved site
Occurring in:
  1. Endolysin; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

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