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Solution structure of 7SK stem-loop 1 with HIV-1 Tat Finland Arginine Rich Motif

X-ray solution scattering
PDB entry 7t1p coloured by chain, ensemble of 10 models, front view.
PDB entry 7t1p coloured by chain, ensemble of 10 models, side view.
PDB entry 7t1p coloured by chain, ensemble of 10 models, top view.
Source organisms:
Assembly composition:
hetero dimer (preferred)
Entry contents: 1 distinct polypeptide molecule
1 distinct RNA molecule

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 11371.71 Å2
Buried surface area: 2126.07 Å2
Dissociation area: 1,063.04 Å2
Dissociation energy (ΔGdiss): -15.85 kcal/mol
Dissociation entropy (TΔSdiss): 9.39 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-168814

Macromolecules

Tat Finland Arginine Rich Motif
Chain: B
Length: 17 amino acids
Theoretical weight: 2.14 KDa
Source organism: HIV-1 06TG.HT008
Expression system: Not provided
InterPro: Immunodeficiency virus transactivating regulatory protein (Tat)
Tat Finland Arginine Rich Motif in PDB entry 7t1p, assembly 1, front view.
Tat Finland Arginine Rich Motif in PDB entry 7t1p, assembly 1, side view.
Tat Finland Arginine Rich Motif in PDB entry 7t1p, assembly 1, top view.
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RNA chain A
Name: RNA (56-MER)
Representative chains: A
Source organism: Homo sapiens [9606]
Expression system: Not provided
Length: 56 nucleotides
Theoretical weight: 17.99 KDa
Rfam: 7SK RNA
RNA (56-MER) in PDB entry 7t1p, assembly 1, front view.
RNA (56-MER) in PDB entry 7t1p, assembly 1, side view.
RNA (56-MER) in PDB entry 7t1p, assembly 1, top view.
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