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Delta (B.1.617.2) SARS-CoV-2 variant spike protein (S-GSAS-Delta) in the 1-RBD-up conformation; Subclassification D12 state

Electron Microscopy
3.4Å resolution
PDB entry 7tp8 coloured by chain, front view.
PDB entry 7tp8 coloured by chain, side view.
PDB entry 7tp8 coloured by chain, top view.
Source organism: Severe acute respiratory syndrome coronavirus 2
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: SARS-CoV-2 post-fusion S2 Spike complex
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Multimeric state: homo trimer
Accessible surface area: 133135.91 Å2
Buried surface area: 38333.25 Å2
Dissociation area: 8,549.37 Å2
Dissociation energy (ΔGdiss): 114.13 kcal/mol
Dissociation entropy (TΔSdiss): 18.9 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-144650
Complex Portal ID: CPX-7043

Macromolecules

Spike glycoprotein
Chains: A, B, C
Length: 1286 amino acids
Theoretical weight: 142.24 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1208; Coverage: 95%)
Gene names: 2, S
Pfam:
InterPro:
Spike glycoprotein in PDB entry 7tp8, assembly 1, front view.
Spike glycoprotein in PDB entry 7tp8, assembly 1, side view.
Spike glycoprotein in PDB entry 7tp8, assembly 1, top view.
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