Function and Biology Details
Reactions catalysed:
GTP + H(2)O = GDP + phosphate
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero 38-mer (preferred)
PDBe Complex ID:
PDB-CPX-130100 (preferred)
Entry contents:
35 distinct polypeptide molecules
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (37 distinct):
Eukaryotic translation initiation factor 5B
Molecule details ›
Chain: 1
Length: 619 amino acids
Theoretical weight: 69.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 619 amino acids
Theoretical weight: 69.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O60841 (Residues: 602-625, 626-1219; Coverage: 51%)
Sequence domains:
Eukaryotic translation initiation factor 1A, X-chromosomal
Molecule details ›
Chain: 4
Length: 90 amino acids
Theoretical weight: 10.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Translation initiation factor 1A / IF-1
Length: 90 amino acids
Theoretical weight: 10.38 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P47813 (Residues: 24-113; Coverage: 63%)
Sequence domains: Translation initiation factor 1A / IF-1
Small ribosomal subunit protein eS1; Small ribosomal subunit protein uS2
Small ribosomal subunit protein uS5
Small ribosomal subunit protein eS4, X isoform
Small ribosomal subunit protein uS3
Small ribosomal subunit protein eS6
Small ribosomal subunit protein eS7
Small ribosomal subunit protein eS8
Small ribosomal subunit protein uS4
Small ribosomal subunit protein uS7
Small ribosomal subunit protein uS17
Small ribosomal subunit protein eS10
Small ribosomal subunit protein uS15
Small ribosomal subunit protein eS12
Small ribosomal subunit protein uS11
Small ribosomal subunit protein uS19
Small ribosomal subunit protein uS9
Small ribosomal subunit protein eS17
Small ribosomal subunit protein uS13
Small ribosomal subunit protein eS19
Small ribosomal subunit protein uS10
Small ribosomal subunit protein uS8
Small ribosomal subunit protein uS12
Small ribosomal subunit protein eS24
Small ribosomal subunit protein eS21
Small ribosomal subunit protein eS25
Small ribosomal subunit protein eS27
Small ribosomal subunit protein eS26
Small ribosomal subunit protein eS28
Small ribosomal subunit protein eS30
Small ribosomal subunit protein uS14
Small ribosomal subunit protein eS31
Small ribosomal subunit protein eS32
Small ribosomal subunit protein RACK1
