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The beta-tubulin folding intermediate I

Source organism: Homo sapiens
Biochemical function: ATP-dependent protein folding chaperone
Biological process: protein folding
Cellular component: extracellular exosome

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF00118
Domain description: TCP-1/cpn60 chaperonin family
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit theta. Showing 1 copy in chain B.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit eta. Showing 1 copy in chain C.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit epsilon. Showing 1 copy in chain D.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit beta. Showing 1 copy in chain E.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit delta. Showing 1 copy in chain F.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit alpha. Showing 1 copy in chain G.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit gamma. Showing 1 copy in chain H.
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00118 (TCP-1/cpn60 chaperonin family) in T-complex protein 1 subunit zeta. Showing 1 copy in chain I.

PF03953
Domain description: Tubulin C-terminal domain
Occurring in:
  1. Tubulin beta chain
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF03953 (Tubulin C-terminal domain) in Tubulin beta chain. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

PF00091
Domain description: Tubulin/FtsZ family, GTPase domain
Occurring in:
  1. Tubulin beta chain
The deposited structure of PDB entry 7trg contains 1 copy of Pfam domain PF00091 (Tubulin/FtsZ family, GTPase domain) in Tubulin beta chain. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR017998
Domain description: Chaperone tailless complex polypeptide 1 (TCP-1)
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR002194
Domain description: Chaperonin TCP-1, conserved site
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR027409
Domain description: GroEL-like apical domain superfamily
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR027410
Domain description: TCP-1-like chaperonin intermediate domain superfamily
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR027413
Domain description: GroEL-like equatorial domain superfamily
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR002453
Domain description: Beta tubulin
Occurring in:
  1. Tubulin beta chain
IPR000217
Domain description: Tubulin
Occurring in:
  1. Tubulin beta chain
IPR002423
Domain description: Chaperonin Cpn60/GroEL/TCP-1 family
Occurring in:
  1. T-complex protein 1 subunit theta
  2. T-complex protein 1 subunit eta
  3. T-complex protein 1 subunit epsilon
  4. T-complex protein 1 subunit beta
  5. T-complex protein 1 subunit delta
  6. T-complex protein 1 subunit alpha
  7. T-complex protein 1 subunit gamma
  8. T-complex protein 1 subunit zeta
IPR012722
Domain description: T-complex protein 1, zeta subunit
Occurring in:
  1. T-complex protein 1 subunit zeta
IPR012719
Domain description: T-complex protein 1, gamma subunit
Occurring in:
  1. T-complex protein 1 subunit gamma
IPR012715
Domain description: T-complex protein 1, alpha subunit
Occurring in:
  1. T-complex protein 1 subunit alpha
IPR012717
Domain description: T-complex protein 1, delta subunit
Occurring in:
  1. T-complex protein 1 subunit delta
IPR012716
Domain description: T-complex protein 1, beta subunit
Occurring in:
  1. T-complex protein 1 subunit beta
IPR012718
Domain description: T-complex protein 1, epsilon subunit
Occurring in:
  1. T-complex protein 1 subunit epsilon
IPR012720
Domain description: T-complex protein 1, eta subunit
Occurring in:
  1. T-complex protein 1 subunit eta
IPR012721
Domain description: T-complex protein 1, theta subunit
Occurring in:
  1. T-complex protein 1 subunit theta
IPR018316
Domain description: Tubulin/FtsZ, 2-layer sandwich domain
Occurring in:
  1. Tubulin beta chain
IPR003008
Domain description: Tubulin/FtsZ, GTPase domain
Occurring in:
  1. Tubulin beta chain
IPR036525
Domain description: Tubulin/FtsZ, GTPase domain superfamily
Occurring in:
  1. Tubulin beta chain
IPR023123
Domain description: Tubulin, C-terminal
Occurring in:
  1. Tubulin beta chain
IPR037103
Domain description: Tubulin/FtsZ-like, C-terminal domain
Occurring in:
  1. Tubulin beta chain
IPR008280
Domain description: Tubulin/FtsZ, C-terminal
Occurring in:
  1. Tubulin beta chain
IPR017975
Domain description: Tubulin, conserved site
Occurring in:
  1. Tubulin beta chain
IPR013838
Domain description: Beta tubulin, autoregulation binding site
Occurring in:
  1. Tubulin beta chain

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