7tyn

Electron Microscopy
2.6Å resolution

Calcitonin Receptor in complex with Gs and salmon calcitonin peptide

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-207680 (preferred)
Entry contents:
6 distinct polypeptide molecules
Macromolecules (6 distinct):
Calcitonin peptide-like domain-containing protein Chain: P
Molecule details ›
Chain: P
Length: 33 amino acids
Theoretical weight: 3.44 KDa
Source organism: Salmo salar
Expression system: Not provided
Calcitonin receptor Chain: R
Molecule details ›
Chain: R
Length: 501 amino acids
Theoretical weight: 58.47 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Chain: A
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Chain: B
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Chain: G
Nanobody 35 Chain: N

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-26188
Expression systems:
  • Not provided
  • Trichoplusia ni
  • Escherichia coli