Assemblies
Assembly Name:
Serine--tRNA ligase, mitochondrial
Multimeric state:
homo dimer
Accessible surface area:
40491.24 Å2
Buried surface area:
8662.57 Å2
Dissociation area:
3,525.58
Å2
Dissociation energy (ΔGdiss):
44.97
kcal/mol
Dissociation entropy (TΔSdiss):
15.43
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-192462
Macromolecules
Chains: A, B
Length: 484 amino acids
Theoretical weight: 54.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: tRNA synthetase class II core domain (G, H, P, S and T)
InterPro:
Length: 484 amino acids
Theoretical weight: 54.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9NP81 (Residues: 35-518; Coverage: 93%)
Pfam: tRNA synthetase class II core domain (G, H, P, S and T)
InterPro:
- Serine-tRNA ligase, type1
- Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm
- Serine-tRNA synthetase, type1, N-terminal domain superfamily
- Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL)
- Serine-tRNA ligase catalytic core domain
- Aminoacyl-tRNA synthetase, class II
- Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
PDBe-KB: UniProt Coverage View:
Q9NP81
Q9NP81
Chains
Domains
Secondary structure
Flexibility predictions
Ligand binding sites
Interaction interfaces