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IOMA class antibody Fab ACS124

X-ray diffraction
1.73Å resolution
PDB entry 7u0k coloured by chain, front view.
PDB entry 7u0k coloured by chain, side view.
PDB entry 7u0k coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-heavy chain and IG-light lambda chain
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Multimeric state: hetero dimer
Accessible surface area: 19325.28 Å2
Buried surface area: 4711.03 Å2
Dissociation area: 2,060.16 Å2
Dissociation energy (ΔGdiss): 17.21 kcal/mol
Dissociation entropy (TΔSdiss): 13.33 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-226473

Macromolecules

IOMA Class antibody ACS124 Light chain
Chain: L
Length: 213 amino acids
Theoretical weight: 22.95 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
InterPro:
IOMA Class antibody ACS124 Light chain in PDB entry 7u0k, assembly 1, front view.
IOMA Class antibody ACS124 Light chain in PDB entry 7u0k, assembly 1, side view.
IOMA Class antibody ACS124 Light chain in PDB entry 7u0k, assembly 1, top view.
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IOMA Class antibody ACS124 Heavy chain
Chain: H
Length: 228 amino acids
Theoretical weight: 24.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
InterPro:
IOMA Class antibody ACS124 Heavy chain in PDB entry 7u0k, assembly 1, front view.
IOMA Class antibody ACS124 Heavy chain in PDB entry 7u0k, assembly 1, side view.
IOMA Class antibody ACS124 Heavy chain in PDB entry 7u0k, assembly 1, top view.
Molecule details ›

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