Mediator-PIC Early (Tail A/B Dimer)
Source organism:
Saccharomyces cerevisiae
Biochemical function:
protein binding
Biological process: positive regulation of transcription initiation by RNA polymerase II
Cellular component: core mediator complex
Biological process: positive regulation of transcription initiation by RNA polymerase II
Cellular component: core mediator complex
Protein families (Pfam)![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF20719 (Mediator complex subunit 16, C-terminal) in Mediator of RNA polymerase II transcription subunit 16. Showing 1 copy in chain L [auth 6].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_6_6_Pfam_PF20719_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF20719 (Mediator complex subunit 16, C-terminal)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 16</span>. Showing 1 copy in chain <span class='highlight'>L [auth 6]</span>.")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF11635 (Mediator complex subunit 16, N-terminal) in Mediator of RNA polymerase II transcription subunit 16. Showing 1 copy in chain L [auth 6].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_6_6_Pfam_PF11635_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF11635 (Mediator complex subunit 16, N-terminal)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 16</span>. Showing 1 copy in chain <span class='highlight'>L [auth 6]</span>.")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF05397 (Mediator complex subunit 15) in Mediator of RNA polymerase II transcription subunit 15. Showing 1 copy in chain K [auth 5] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7uil_5_5_Pfam_PF05397_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF05397 (Mediator complex subunit 15)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 15</span>. Showing 1 copy in chain <span class='highlight'>K [auth 5]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF18535 (Gal11 activator-binding domain (ABD1)) in Mediator of RNA polymerase II transcription subunit 15. Showing 1 copy in chain K [auth 5] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7uil_5_5_Pfam_PF18535_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF18535 (Gal11 activator-binding domain (ABD1))</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 15</span>. Showing 1 copy in chain <span class='highlight'>K [auth 5]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF16987 (KIX domain) in Mediator of RNA polymerase II transcription subunit 15. Showing 1 copy in chain K [auth 5] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7uil_5_5_Pfam_PF16987_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF16987 (KIX domain)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 15</span>. Showing 1 copy in chain <span class='highlight'>K [auth 5]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF08638 (Mediator complex subunit MED14) in Mediator of RNA polymerase II transcription subunit 14. Showing 1 copy in chain J [auth 4] (this domain is out of the observed residue ranges!).](https://www.ebi.ac.uk/pdbe/static/entry/7uil_4_4_Pfam_PF08638_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF08638 (Mediator complex subunit MED14)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 14</span>. Showing 1 copy in chain <span class='highlight'>J [auth 4]</span> (this domain is out of the observed residue ranges!).")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF08689 (Mediator complex subunit Med5) in Mediator of RNA polymerase II transcription subunit 5. Showing 1 copy in chain I [auth 3].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_3_3_Pfam_PF08689_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF08689 (Mediator complex subunit Med5)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 5</span>. Showing 1 copy in chain <span class='highlight'>I [auth 3]</span>.")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF11593 (Mediator complex subunit 3 fungal) in Mediator of RNA polymerase II transcription subunit 3. Showing 1 copy in chain H [auth 2].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_2_2_Pfam_PF11593_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF11593 (Mediator complex subunit 3 fungal)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 3</span>. Showing 1 copy in chain <span class='highlight'>H [auth 2]</span>.")
![The deposited structure of PDB entry 7uil contains 2 copies of Pfam domain PF11214 (Mediator complex subunit 2) in Mediator of RNA polymerase II transcription subunit 2. Showing 1 copy in chain G [auth 1].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_1_1_Pfam_PF11214_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 2 copies of Pfam domain <span class='highlight'>PF11214 (Mediator complex subunit 2)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 2</span>. Showing 1 copy in chain <span class='highlight'>G [auth 1]</span>.")
![The deposited structure of PDB entry 7uil contains 1 copy of Pfam domain PF10744 (Mediator of RNA polymerase II transcription subunit 1) in Mediator of RNA polymerase II transcription subunit 1. Showing 1 copy in chain M [auth a].](https://www.ebi.ac.uk/pdbe/static/entry/7uil_7_a_Pfam_PF10744_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>7uil</span> contains 1 copy of Pfam domain <span class='highlight'>PF10744 (Mediator of RNA polymerase II transcription subunit 1)</span> in <span class='highlight'>Mediator of RNA polymerase II transcription subunit 1</span>. Showing 1 copy in chain <span class='highlight'>M [auth a]</span>.")
InterPro annotations