7ukm

Electron Microscopy
3.03Å resolution

Cryo-EM structure of Antibody 12-19 in complex with prefusion SARS-CoV-2 Spike glycoprotein

Released:
Entry authors: Casner RG, Shapiro L
Related structures: EMD-26584

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
PDBe Complex ID:
PDB-CPX-230847 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1273 amino acids
Theoretical weight: 141.21 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 1-1273; Coverage: 100%)
Gene names: 2, S
Sequence domains:
12-19 Fab Heavy Chain Chains: H, M, X
Molecule details ›
Chains: H, M, X
Length: 133 amino acids
Theoretical weight: 14.96 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
12-19 Fab Light Chain Chains: L, N, Y
Molecule details ›
Chains: L, N, Y
Length: 112 amino acids
Theoretical weight: 12.39 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.03Å
Relevant EMDB volumes: EMD-26584
Expression system: Homo sapiens