› 7upb

Electron Microscopy
3Å resolution

Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H1

Released:
DOI: 10.2210/pdb7upb/pdb
PDB entry 7upb coloured by chain, front view.
PDB entry 7upb coloured by chain, side view.
PDB entry 7upb coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Byrne PO, Fisher BE, Ambrozak DR, Blade EG, Tsybovsky Y, Graham BS, McLellan JS, Loomis RJ
OpenAccess logo Nat Commun 14 1494 (2023)
PMID: 36932063
Related structures: EMD-26660

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212752 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Fusion glycoprotein F0 Chains: A, D, G
Molecule details ›
Chains: A, D, G
Length: 475 amino acids
Theoretical weight: 52.3 KDa
UniProt:
  • Canonical: Q9IH63 (Residues: 1-475; Coverage: 86%)
Gene name: F
Sequence domains: Fusion glycoprotein F0
Fab 1H1 heavy chain Chains: B, C, H
Molecule details ›
Chains: B, C, H
Length: 120 amino acids
Theoretical weight: 13.19 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
Fab 1H1 light chain Chains: E, F, L
Molecule details ›
Chains: E, F, L
Length: 106 amino acids
Theoretical weight: 11.68 KDa
Source organism: Mus musculus
Expression system: Homo sapiens

Ligands and Environments

1 bound ligand:
Ligand NAG 3 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3Å
Relevant EMDB volumes: EMD-26660
Expression system: Homo sapiens

Quick links