› 7uzj

Electron Microscopy
3.3Å resolution

Rat Kidney V1 complex with SidK and NCOA7B, State 1

Released:
DOI: 10.2210/pdb7uzj/pdb
PDB entry 7uzj coloured by chain, front view.
PDB entry 7uzj coloured by chain, side view.
PDB entry 7uzj coloured by chain, top view.
Source organisms:
Entry authors: Abbas YM, Rubinstein JL
Related structures: EMD-26913

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero icosamer (preferred)
PDBe Complex ID:
PDB-CPX-235502 (preferred)
Entry contents:
10 distinct polypeptide molecules
Macromolecules (10 distinct):
H(+)-transporting two-sector ATPase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 617 amino acids
Theoretical weight: 68.34 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: D4A133 (Residues: 31-647; Coverage: 95%)
Gene name: Atp6v1a
Sequence domains:
V-type proton ATPase subunit B, brain isoform Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 511 amino acids
Theoretical weight: 56.61 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P62815 (Residues: 1-511; Coverage: 100%)
Gene names: Atp6b2, Atp6v1b2, Vat2
Sequence domains:
V-type proton ATPase subunit C 1 Chain: G
Molecule details ›
Chain: G
Length: 382 amino acids
Theoretical weight: 43.96 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: Q5FVI6 (Residues: 1-382; Coverage: 100%)
Gene name: Atp6v1c1
Sequence domains: V-ATPase subunit C
V-type proton ATPase subunit D Chain: H
Molecule details ›
Chain: H
Length: 247 amino acids
Theoretical weight: 28.36 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: Q6P503 (Residues: 1-247; Coverage: 100%)
Gene name: Atp6v1d
Sequence domains: ATP synthase subunit D
V-type proton ATPase subunit E 1 Chains: I, J, K
Molecule details ›
Chains: I, J, K
Length: 226 amino acids
Theoretical weight: 26.17 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: Q6PCU2 (Residues: 1-226; Coverage: 100%)
Gene name: Atp6v1e1
Sequence domains: ATP synthase (E/31 kDa) subunit
V-type proton ATPase subunit F Chain: L
Molecule details ›
Chain: L
Length: 119 amino acids
Theoretical weight: 13.39 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: P50408 (Residues: 1-119; Coverage: 100%)
Gene names: Atp6s14, Atp6v1f, Vatf
Sequence domains: ATP synthase (F/14-kDa) subunit
V-type proton ATPase subunit G Chains: M, N, O
Molecule details ›
Chains: M, N, O
Length: 118 amino acids
Theoretical weight: 13.73 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: B2GUV5 (Residues: 1-118; Coverage: 100%)
Gene names: Atp6v1g1, rCG_55259
Sequence domains: Vacuolar (H+)-ATPase G subunit
V-type proton ATPase subunit H Chain: P
Molecule details ›
Chain: P
Length: 483 amino acids
Theoretical weight: 55.94 KDa
Source organism: Rattus norvegicus
UniProt:
  • Canonical: A0A0G2K9J2 (Residues: 1-428; Coverage: 98%)
Gene name: Atp6v1h
Sequence domains:
Type IV secretion protein Dot Chains: Q, R, S
Molecule details ›
Chains: Q, R, S
Length: 280 amino acids
Theoretical weight: 32.15 KDa
Source organism: Legionella pneumophila
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5ZWW6 (Residues: 1-280; Coverage: 49%)
Gene name: lpg0968
Nuclear receptor coactivator 7B Chain: T
Molecule details ›
Chain: T
Length: 221 amino acids
Theoretical weight: 25.6 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
Ligand ADP 1 x ADP
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.3Å
Relevant EMDB volumes: EMD-26913
Expression system: Escherichia coli

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